Endocrine: Obesity Flashcards

1
Q

Obesity in what area of the body has the following effects?

  • increased risk for cardiometabolic disease
  • decreased life expectancy
A

abdominal obesity

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2
Q

Waist circumference is measured for pts with BMI between…

A

25-35

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3
Q

A waist circumference of _____ in men and ______ in women confers increased CV risk

A

40+ men

35+ women

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4
Q

This disease is defined as…

Chronic disease with ↑ body fat, adipose dysfunction resulting in adverse metabolic, biomechanical, psychosocial health consequences

A

obesity

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5
Q

What labs should be considered for obesity? (4)

A

fasting glucose/Hba1c

TSH

Liver Enzymes

Fasting lipids

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6
Q

What should the initial goal of weight loss be for obesity?

A

5-7% of body weight

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7
Q

Weight loss of _____% or morereduces risks associated with obesity…

A

> 5%

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8
Q

The following MNT diets are effective for…

DASH
Mediterranean
CHO Counting
Sugar limiting

A

T2DM

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9
Q

The following MNT diets are effective for…

DASH
Mediterranean
low sodium

A

CVD

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10
Q

The following MNT diets are effective for…

DASH
Renal

A

CKD

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11
Q

sedentary lifestyle is a strong predictor of…

A

mortality

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12
Q

The below are two immediate effects of:

↓ Anxiety & BP

↑ Sleep, cognitive fxn, insulin sensitivity

A

exercise in obese pts.

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13
Q

What are 3 long-term benefits of exercise?

A

↑ CardioPulm Fitness, strength

↓ BP, depression

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14
Q

how many minutes of moderate exercise are recommended weekly?

(moderate = talk, no singing)

A

150-300 min

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15
Q

how many minutes of vigorous exercise is recommended in lieu of moderate…

(vigorous = few words)

A

75-150

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16
Q

How many days a week should strength training occur?

A

2+

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17
Q

What is the FITT protocol for exercise?

frequency, intensity, time, type

A

5+ days
modorate-vigorous
30+ minutes
major muscle groups, start w. walking

18
Q

Who should be screened for obesity?

A

all adults

19
Q

Intensive, multicomponent, behavioral intervention for obesity (BMI 30+) includes what frequency of sessions?

A

12-26/yr,

2 sessions monthly x 3+ mo

20
Q

What are the 5 As of counseling?

A
ask/address
advise
assess
assist
arrange
21
Q

What Tx?

BMI 25 to 29.9 with no CVD risk factors or comorbidities

A

diet & exercise counseling

low risk

22
Q

What tx?

BMI 25 to 29.9 AND 1+ CVD risk factors

BMI 30 to 34.9

A

Intensive, multicomponent behavioral modification

+/- drug therapy

23
Q

What tx?

BMI 35 to 40, BMI > 40

A

Intensive, multicomponent behavioral modification

+/- drug therapy

+/- bariatric surgery

24
Q

1st line tx for obesity is always…

A

lifestyle program

25
Q

if weight loss on lifestyle modification program is < 5% in 3-6 months, what can you consider?

A

drug therapy

26
Q

What is the goal of drug therapy in obesity? (3)

A

4-8% body weight loss, improve health, minimize adverse effects

27
Q

If a patient has a BMI of 30+ or > 27 with comorbidity, what can you consider adding to the tx regimen?

A

drug therapy

28
Q

Which obesity drug?

Inhibits pancreatic lipase

May decrease fat soluble vitamin absorption (ADEK)

A

orlistat

29
Q

Which obesity drug?

GLP-1 Receptor Agonist

SQ admin

DOC w. T2DM

A

liraglutide

30
Q

Which obesity drug?

Selective Serotonin Agonist

Decrease Appetite

Limited safety data

A

Lorcaserin

31
Q

This obesity drug should be avoided w. HTN, CAD, Hyperthyroid

A

phentermine/topiramate

32
Q

Which obesity drug?

Sympathomimetic

Most prescribed

most SFx

avoid w. HTN, CAD, Hyperthyroid

A

phentermine

33
Q

What four factors should be monitored during drug therapy for obesity?

A

weight, BP, HR, SFx

34
Q

Neuropsych sfx can be present with what two drugs?

A

lorcaserin, phentermine-topiramate

35
Q

If weight loss of 4-5% is not achieved after 3 mo of obesity drug therapy, what can you consider?

A

switching meds

36
Q

hCG for weight loss requires a diet of ____ and is/isn’t a recommended therapy

A

500kcal

not recommended

37
Q

What are three bariatric surgical procedures?

A

sleeve gastrectomy

roux en Y gastric bypass

Adjustable gastric band

38
Q

The below are contraindications for…

Eating disorder
Untreated mental illness
EtOH, drug abuse
Coagulopathy
Severe cardiac disease
Inability to comply
A

bariatric surgery

39
Q

The below are therapeutic effects accomplished via…

Restriction, malabsorption, decrease appetite via hormone modulation

A

bariatric surgery

40
Q

3 indications for bariatric surg.

A

BMI 40+

35-29.9 + 1+ comorbidity

30-34.9 w/ uncontrolled T2DM or Metabolic Syndrome