Heart Development Flashcards
What germ layer does the heart develop from?
Cardiogenic mesoderm
What is the condition when the heart is pointing the wrong way?
Dextrocardia
When and how do the atria and ventricles divide?
Endocardial cushions bulge out at 28 days
What is the consequence of atrial septum defects?
Hole instead of valve leads to RV hypertrophy
What are acyanotic congenital heart defects?
ASD, VSD, patent ductus arteriosus, coarctation of the aorta
How is patent ductus arteriosus treated?
Ibuprofen then surgery
What results from pre ductal coarctation?
Ductus arteriosus persists
What results from post ductal coarctation?
Collateral circulation must be established
What are cyanotic lesions?
Deoxygenated blood bypasses the lungs.
What is tetralogy of Fallot?
Rare, 4 defects. VSD, overriding aorta, pulmonary stenosis, RV hypertrophy
What is persistent truncus arteriosus?
Spiral septum doesn’t form-> large VSD. Progressive HF
What is transposition of the great vessels?
Conotrucal septum fails to follow spiral course. Immediate surgical intervention
What does the ductus arteriosus fibrose to form?
Ligamentum arteriosum
What does the ductus venosus fibrose to form?
Ligamentum venosus
What does the umbilical vein fibrose to form?
Ligamentum teres
