Heamatology buzzwords Flashcards

1
Q

What condition does a pepper pot skull/lytic lesions indicate?

A

Myeloma

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2
Q

What does congo red staining allow you to see?

A

amyloid deposition of biopsy tissue in myeloma & AA amyloidosis

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3
Q

What are Reed-Sternberg cells pathogneumonic of?

A

Hogkin’s lymphoma

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4
Q

What is the Philaphelphia chromosome (9;22 Translocation) associated with?

A

CML

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5
Q

What do atypical lymphocytes on a blood film suggest?

A

Viral infection e.g. EBV

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6
Q

What do Auer rods suggest on a blood film?

A

AML

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7
Q

What condition are bence-jones protein associated with?

A

Multiple Myeloma

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8
Q

A patient presents with the complain of being itchy after a hot bath. What condition do you suspect?

A

Polycythaemia Rubra Vera

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9
Q

What condition is associated with an 8;14 translocation?

A

Burkitt’s llymphoma

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10
Q

What condition does alcohol make worse?

A

Hodgkins lymphoma

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11
Q

What condition has haemarthrosis as a complication?

A

Haemophilia

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12
Q

What condition has reduced levels of factor IX with christmas disease?

A

Haemophilia B

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13
Q

What condition has reduced levels of factor VIII & an increased APTT?

A

Haemophilia A

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14
Q

What is a shillings test used to show?

A

B12 deficiency

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15
Q

What does smudge cells on a blood film suggest?

A

CLL

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16
Q

JAK-2 mutation is mainly associated with what conditions?

A

PRV or essential thrombocythemia

17
Q

NBT test is used for what condition?

A

CGD

18
Q

Positive Schumm’s test suggests ?

A

Intravascualr Haemolytic anaemia

19
Q

A hair-on-end skull x-ray appearance suggests?

A

Major Beta-thalassaemia

20
Q

Bite cell, blister cells & heinz bodies suggest what?

A

G6PD deficiency

21
Q

Russell Bodies suggest what?

A

Chronic Inflammaiton

22
Q

Schistocytes suggest what?

A

intravascular haemolysis