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Neuro Block 2-RG > Headaches > Flashcards

Headaches Flashcards

1
Q

What is the pathophysiology of tension headaches?

A

compression of the greater occipital nerve

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2
Q

Tension headaches: unilateral or bilateral?

A

bilateral

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3
Q

What is the treatment for tension headaches?

A

analgesics and biofeedback

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4
Q

What is the pathophysiology of cluster headaches?

A

hypothalamic activation of trigeminovascular autonomic system

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5
Q

Describe the pain in a cluster headache

A

severe unilateral pressure in orbital, supraorbital, or temporal region

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6
Q

What is the treatment for cluster headaches?

A

supplemental oxygen and sumatriptan

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7
Q

What is the pathophysiology of migraine headaches?

A

unknown, may be cortical depression

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8
Q

What are the symptoms of a migraine headache?

A

unilateral throbbing pain that may last hours or days

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9
Q

If someone who has migraines with aura, what do you absolutely not want to give them?

A

oral contraceptives

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10
Q

What is the first-line treatment of migraines?

A

triptans

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11
Q

What is the chemical abbreviation for serotonin?

A

5-HT

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12
Q

What is serotonin synthesized from?

A

tryptophan

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13
Q

What enzyme metabolizes serotonin?

A

monoamine oxygenase (MAO)

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14
Q

Elevated 5-HT levels may preclude what event?

A

migraine headache

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15
Q

What may cause a migraine headache with relation to serotonin?

A

vasoconstriction

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16
Q

Does 5-HT cause vasoconstriction or dilation?

A

vasoconstriction

17
Q

Triptans work how?

A

agonize 5-HT1B and 5-HT1D receptors causing vasoconstriction and decreasing pro-inflammatory nucleopeptide release

18
Q

What are the actions of the 5-HT1B and 5-HT1D receptors?

A

increase K+ permeability and decrease Ca2+ permeability

19
Q

Where are 5-HT1B and 5-HT1D receptors found?

A

presynaptic neuron and postsynaptic neuron, decrease release on presynaptic neuron

Neuro Block 2-RG (23 decks)

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