Brain Neurotransmitter Systems Flashcards

1
Q

What type of ion channel is the GABA channel?

A

Cl-

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2
Q

Two types of channels

A

ionotropic (fast)

metatropic (slow–G-protein coupled)

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3
Q

GABA: inhibitory or excitatory?

A

inhibitory

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4
Q

Postsynaptic glutamate receptors: inhibitory or excitatory

A

excitatory

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5
Q

Presynaptic glutamate receptors: inhibitory or excitatory?

A

inhibitory

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6
Q

Glycine as NT

A

inhibitory in CNS

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7
Q

Action of nAChR

A

open sodium channel

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8
Q

Action of mAChR

A

metabotropic improves memory (inhibitory)

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9
Q

Two types of dopamine receptors

A

D1 and D2

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10
Q

D1 receptors + disease

A

Gs (stimulatory)
increases cAMP production
Tourrette’s

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11
Q

D2 receptors + disease

A

Gi (inhibitory)
decreases cAMP production
Parkinsons

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12
Q

How does norepinephrine act on alpha-2 receptors?

A

increases K+ conductance

hyperpolarizes cells

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13
Q

Agonists of norepinephrine on alpha-2 receptors

A

muscle spasmalytics

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