Hartfalen Flashcards

1
Q

Def Hartfalen

A

Syndroom: SoB/moeheid + in rust/inspanning +objectieve aanw (LVEF) + verbetering bij OMT

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2
Q

Def asymp LV dys

A

Min pompfunctie z/ Sx (wel prec HF)

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3
Q

Def acuut HF

A

De novo HF/acute verslechtering CHF - > acuut LOe e/o cardiogene shock

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4
Q

Def Cardiogene Shock

A

Hypotensie + oligurie + perif vasoconstrictie

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5
Q

Mortaliteit cardiogene shock

A

50%

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6
Q

Def systolisch HF

A

Sx HF + afgen LVEF (35-40%)

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7
Q

Def diastolisch HF

A

Sx HF bij normale LVEF (>45%). E/ verminderde relaxatie l/t stijg EDP LV l/’t stijg EDP LA l/t alveolair LOe

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8
Q

NYHA classificatie

A

NYHA I: geen Sx. NYHA II: Sx bij forse inspan. NYHA III: Sx bij matige inspan. NYHA IV: Sx in rust

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9
Q

def HF m/ preserved EF

A
  • Sx
  • LVEF > 50%
  • Verhoogd NAP
  • 1v2: relevant strucutreel prob (LVF e/o LAE) OF diastolische dysf
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10
Q

def HF m/ midrange EF

A
  • Sx
  • LVEF 40-49%
  • Verhoogd NAP
  • 1v2: relevant strucutreel prob (LVF e/o LAE) OF diastolische dysf
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11
Q

def HF m/ reduced EF (HFrEF)

A
  • Sx

- LVEF <40%

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12
Q

Etiologie HF

A

ICH, myocarditis, CM, druk (HT, AKS), volume (A/MKI, anemie, Hthyr)

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13
Q

Sx HF (typisch)

A

SoB, orthopneu, noct dyspneu, vermin. inspanningstol, vermoeidheid, bilateraal enkeloedeem. Verh jug ven p, hepatojugulaire reflux, 3e harttoon.

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14
Q

Dx algoritme: Assessment of HF Probability

A

1) VG: MI, HT, orthopneu, diuretica gebruik
2) LO: crep, oedeem, ruis, JVDil, laterale apicale beat
3) ECG
>1 PRESENT –> echo

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15
Q

NT-proBNP cutoff?

A

> 125 pg/ml

als positief echo

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16
Q

Tx algoritme HFrEF

A
Overal
-diurectica
-als LVEF <35/VT/VF --> implant ICD
Daarnaast
1) ACEi + BB
2) Add MR antagonist (spiro)
17
Q

CRT als?

A

QRS > 130 ms

18
Q

Werkingsmechanisme Ivabradine

A

<>

IIa/B

19
Q

Bij resistente Sx

A

Digoxine, H-ISDN, LVAD, Transplant

20
Q

Werkingsmechanisme ARNI’s (sacubitril/valsartan)

A

<>

21
Q

Sx linksfalen

A

orthopneu, noct dyspneu, crep, bilat oedeem.

22
Q

Sx rechtsfalen

A

Jug ven dilatatie, perifeer oedeem, oligurie, nauwe PP, sufheid.

23
Q

Sx rechtsfalen: LAB

A

metabole acidose, lactaat (h), creat (h)

24
Q

Opvang pt verdenking AHF

A
  1. cardiogene shock? (circ support)
  2. Vent? (O2 <90%)
    3) Aetiologie? (CHAMP)
25
Q

acronym CHAMP

A
  • aCs
  • Ht
  • Arritmie
  • Mechanism
  • Pe
26
Q

Workop AHF

A
  • NT-proBNP,
  • ECG, CXR
  • lab (tropo, creat, ureum, Na/K, gluc, VBB, TSH, ALA/ASAT)
  • ECHO
27
Q

Tx AHF
“Wet” & Warm.
N tot (H) SBD

A

hypertensie? –> vasodilator + diureticum

Congestie? –> diureticum + vasodilator + ultrafiltraat

28
Q

Tx “Wet & Cold”

A

SBD <90?
J: inotropie + (ref–> vasopres) + diuretica (na herstel perf) + mechanism
N: vasodilator + diuretica + (evt inotropie)

29
Q

Tx “Dry & Cold”

hypoperfused, hypovolemic

A
  • consider fluid challange

- consider inotropie

30
Q

HF bij volumeoverbelasting

A

LV dilatatie –> vullingsdruk (h),

31
Q

HF bij drukoverbelasting

A

diast. dysf. –> LVH (+ parox aryth + ischemie)

32
Q

E/ RVHF?

A

COPD, RA, chon LE, ConHZ, RVinfarct. (ook door backward failure)

33
Q

niet med adviezen

A

educatie
water-zoutbeperking (1500-2000ml 2-5mg dag).
dagelijks wegen
dagelijks bewegen

34
Q

effect ACEi in HF

A

min. H20-Na+ ret; LVH;SZS, Tachyaritmien.

korte kreatstijging 10%

35
Q

effect BB in HF

A

min. morb/mort.
mech: chron SZS (-),
(start low, go slow)

36
Q

Aldosteron antagonisten

A

min. H2O+Na+ ret; plaatjesaggr; SZS; remoddeling; endotheeldis; collageenvorming

37
Q

Ratio ARB ipv ACEi bij HF

A

ACEi remt effect ATII onvoldoende, ARB doet dit direct.

ind: ipv ACEi of als tovoeging bij (NYHA II-III)

38
Q

indicatie digoxine in Tx HF

A

1) ChronHF + AF + Freq >100/min

2) Sx bij optimaal gebruik diu + ACEi + BB + ARB