Hartfalen Flashcards

1
Q

Def Hartfalen

A

Syndroom: SoB/moeheid + in rust/inspanning +objectieve aanw (LVEF) + verbetering bij OMT

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2
Q

Def asymp LV dys

A

Min pompfunctie z/ Sx (wel prec HF)

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3
Q

Def acuut HF

A

De novo HF/acute verslechtering CHF - > acuut LOe e/o cardiogene shock

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4
Q

Def Cardiogene Shock

A

Hypotensie + oligurie + perif vasoconstrictie

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5
Q

Mortaliteit cardiogene shock

A

50%

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6
Q

Def systolisch HF

A

Sx HF + afgen LVEF (35-40%)

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7
Q

Def diastolisch HF

A

Sx HF bij normale LVEF (>45%). E/ verminderde relaxatie l/t stijg EDP LV l/’t stijg EDP LA l/t alveolair LOe

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8
Q

NYHA classificatie

A

NYHA I: geen Sx. NYHA II: Sx bij forse inspan. NYHA III: Sx bij matige inspan. NYHA IV: Sx in rust

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9
Q

def HF m/ preserved EF

A
  • Sx
  • LVEF > 50%
  • Verhoogd NAP
  • 1v2: relevant strucutreel prob (LVF e/o LAE) OF diastolische dysf
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10
Q

def HF m/ midrange EF

A
  • Sx
  • LVEF 40-49%
  • Verhoogd NAP
  • 1v2: relevant strucutreel prob (LVF e/o LAE) OF diastolische dysf
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11
Q

def HF m/ reduced EF (HFrEF)

A
  • Sx

- LVEF <40%

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12
Q

Etiologie HF

A

ICH, myocarditis, CM, druk (HT, AKS), volume (A/MKI, anemie, Hthyr)

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13
Q

Sx HF (typisch)

A

SoB, orthopneu, noct dyspneu, vermin. inspanningstol, vermoeidheid, bilateraal enkeloedeem. Verh jug ven p, hepatojugulaire reflux, 3e harttoon.

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14
Q

Dx algoritme: Assessment of HF Probability

A

1) VG: MI, HT, orthopneu, diuretica gebruik
2) LO: crep, oedeem, ruis, JVDil, laterale apicale beat
3) ECG
>1 PRESENT –> echo

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15
Q

NT-proBNP cutoff?

A

> 125 pg/ml

als positief echo

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16
Q

Tx algoritme HFrEF

A
Overal
-diurectica
-als LVEF <35/VT/VF --> implant ICD
Daarnaast
1) ACEi + BB
2) Add MR antagonist (spiro)
17
Q

CRT als?

A

QRS > 130 ms

18
Q

Werkingsmechanisme Ivabradine

19
Q

Bij resistente Sx

A

Digoxine, H-ISDN, LVAD, Transplant

20
Q

Werkingsmechanisme ARNI’s (sacubitril/valsartan)

21
Q

Sx linksfalen

A

orthopneu, noct dyspneu, crep, bilat oedeem.

22
Q

Sx rechtsfalen

A

Jug ven dilatatie, perifeer oedeem, oligurie, nauwe PP, sufheid.

23
Q

Sx rechtsfalen: LAB

A

metabole acidose, lactaat (h), creat (h)

24
Q

Opvang pt verdenking AHF

A
  1. cardiogene shock? (circ support)
  2. Vent? (O2 <90%)
    3) Aetiologie? (CHAMP)
25
acronym CHAMP
- aCs - Ht - Arritmie - Mechanism - Pe
26
Workop AHF
- NT-proBNP, - ECG, CXR - lab (tropo, creat, ureum, Na/K, gluc, VBB, TSH, ALA/ASAT) - ECHO
27
Tx AHF "Wet" & Warm. N tot (H) SBD
hypertensie? --> vasodilator + diureticum | Congestie? --> diureticum + vasodilator + ultrafiltraat
28
Tx "Wet & Cold"
SBD <90? J: inotropie + (ref--> vasopres) + diuretica (na herstel perf) + mechanism N: vasodilator + diuretica + (evt inotropie)
29
Tx "Dry & Cold" | hypoperfused, hypovolemic
- consider fluid challange | - consider inotropie
30
HF bij volumeoverbelasting
LV dilatatie --> vullingsdruk (h),
31
HF bij drukoverbelasting
diast. dysf. --> LVH (+ parox aryth + ischemie)
32
E/ RVHF?
COPD, RA, chon LE, ConHZ, RVinfarct. (ook door backward failure)
33
niet med adviezen
educatie water-zoutbeperking (1500-2000ml 2-5mg dag). dagelijks wegen dagelijks bewegen
34
effect ACEi in HF
min. H20-Na+ ret; LVH;SZS, Tachyaritmien. | korte kreatstijging 10%
35
effect BB in HF
min. morb/mort. mech: chron SZS (-), (start low, go slow)
36
Aldosteron antagonisten
min. H2O+Na+ ret; plaatjesaggr; SZS; remoddeling; endotheeldis; collageenvorming
37
Ratio ARB ipv ACEi bij HF
ACEi remt effect ATII onvoldoende, ARB doet dit direct. | ind: ipv ACEi of als tovoeging bij (NYHA II-III)
38
indicatie digoxine in Tx HF
1) ChronHF + AF + Freq >100/min | 2) Sx bij optimaal gebruik diu + ACEi + BB + ARB