Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BPT Written > Haemotology > Flashcards

Haemotology Flashcards

1
Q

Coagulation test most sensitive to presence of Dabigatran?

A

Thrombin clotting time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Changes that occur in the haemostatic system in chronic liver disease

A

Decreased protein C level
Reduced platelet count
Elevated von Willebrand factor levels
Decreased factor VII levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anaemia of chronic disease

A

Low serum iron levels
Reduced red cell survival
Increased hepcidin levels
Decreased erythroid response to EPO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

BCR-ABL t(9;22)

A

CML

Philadelphia chromosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Cyclin D1 t(11;14)

A

Mantle Cell Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

C-myc t(8;14)

A

Burkitt Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

JAK 2 V617F

A

Polycythemia Vera
Essential thrombocytopenia
Idiopathic myelofibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

JAK2 Exon 12

A

Myeloproliferative syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

cKIT D816V

A

Systemic mastocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Role of Hepcidin in modulating iron balance

A

Hepcidin acts to decrease intestinal iron absorption by causing the down regulation of ferroportin on the basolateral membrane of enterocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

t(8;21)

A

AML

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

t(9;22)

A

Philadelphia chromosome
Creates a BCL-ABL1 fusion gene that codes for a constitutively active TKR
Present in 95% CML
Poor prognostic indicator in ALL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

t(11;14)

A

Mantle Cell Lymphoma
C5 positive / CD23 negative
Poor prognosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

t(15;17)

A

Acute promyelocytic leukaemia (APML)

Responds to trans retinoic acid (vitamin A)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

t(12;15)

A

Secretory Breast Cancer - rare; good outcome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

t(11;22)

A

Ewing Sarcoma

17
Q

t(8;14)

A

Burkitt’s Lymphoma

18
Q

t(14;18)

A

Follicular lymphoma

19
Q

Gene mutation in essential thrombocytosis

A

JAK2
CALR (calreticulin)
MPL

BPT Written (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions