Haemophilus and Histophilus Flashcards
What bacterium causes Glasser Disease in pigs?
Haemophilus parasuis
What does H. parasuis look like?
Gram neg bacilli to coccobacilli
T/F: Glasser Disease, caused by H. parasuis is strictly an exogenous infection.
FALSE: H. parasuis is a facultative pathogen and commensal of the mucosa in pigs
T/F: H. parasuis infection can happen between 2 weeks - 4 months of age, but is most common around weaning?
TRUE
Septicemia caused by Haemophilus parasuis can affecct the pig in what 2 ways?
Meningitis (CNS signs)
Polyserositis/Polyarthritis (peritonitis, pleuritis)
How and when are antibiotics administered for an H. parasuis infection?
Administered IM at the outbreak of infection, and ALL piglets in the litter are treated.
What is a special consideration when culturing Haemophilus parasuis?
NAD dependent
T/F: The best way to guarantee prevention of H. parasuis and Glasser Disease in pigs is to vaccinate.
FALSE: the vaccine sorta sucks and isn’t always successful
What species of Haemophilus is present in healthy cats, but can cause pneumonia if chronic, and conjunctivitis?
Haemophilus felis
T/F: Haemophilus infections in both pigs and cats are fairly common.
FALSE: both are rare
What Histophilus species is an obligate symbiont of ruminants and colonizes the mucosal surfaces of the urogenital tract?
Histophilus somnei
What are the symptoms of Histophilus somnei infection in ruminants? (there are a lot)
Septicemia CNS (Sleepers dz) Arthritis Retinitis Myocarditis Mastitis Abortion
What disease is caused by Histophilus somnei and is characterized by CNS symptoms and a blood clot in the brain?
Sleepers disease
What are the 4 virulence factors of Histophilus somnei?
LOS - lipooligosaccharides
OMPs
Host cell interactions
Biofilms
Which virulence factor of H. somnei aids with immune evasion and complement resistance?
Lipooligosaccharides (LOS)
