E. coli Flashcards
E. coli is lactose ______ and oxidase ______.
Lactose positive
Oxidase negative
What is the bacterium that causes the most nonsocomial infections in hospital patients?
E. coli
Does E. coli live in the environment?
Nope, just in the GI tract
Types of E. coli infections found in pigs
ETEC - enterotoxigenic VTEC - verotoxigenic EPEC - enteropathogenic UTI MMA - mastitis Septicemia
ETEC affects pigs of what age?
Neonates –> weaning (“weaning diarrhea”)
What is the determining factor that causes ETEC disease in piglets?
Break in equilibrium between maternal immunity and infection pressure
Important receptors involved in ETEC infection in pigs
Neonate: F4, F5, F6, F41
Up until 4wks: F4
Weaning age: F4, F18
Toxins involved in ETEC in pigs
LT
STa
STb
EAST1
Symptoms of ETEC in pigs?
Watery diarrhea
V smelly feces
*In older animals, white/gray stool
VTEC affects pigs of what age?
3 weeks post weaning
What is the adhesion factor associated with VTEC in pigs?
F18
What is the disease associated with VTEC in pigs and what are the symptoms?
Edema disease: CNS symptoms, swollen eyelids, hoarse, dyspnea.
Multiple pigs affected!
*diarrhea when mixed infection with ETEC
What is the adhesion factor associated with VTEC/Edema disease?
F18
Treatments for Edema disease/VTEC:
Fasting
Increase peristalsis
Antimicrobials for those not yet showing signs
Prevention of VTEC:
Reduce stress
Increase fiber
Feed organic acids and zinc
Vaccinate (recombinant) at 4 days
What method of intimate attachment/invasion does EPEC use?
eae
T3SS needle and injection of effector proteins
Diagnosis of EPEC
PCR for detection of eae intimin gene
What is the most important bacterium in UTI?
E. coli
What is the treatment plan for pigs with UTI?
Culling (fertility problems) or try Abx for 3 weeks
T/F: Metritis-Mastitis-Agalactiae (MMA) and Post Partum Dysgalactiae Syndrome (PPDS) are only caused by E. coli?
FALSE: They can also be hereditary/hormonal, or a result of the pig feed.