Haemophilia Flashcards
1
Q
What causes haemophilia A?
A
A lack of factor VIII
2
Q
What inheritance pattern is haemophilia?
A
X linked recessive
3
Q
How does haemophilia present?
A
- Haemarthrosis
- Haematosis (in muscles causes nerve palsies and compartment syndrome)
4
Q
What will blood tests show in haemophilia A?
A
Prolonged APTT
Reduced factor VIII assay
Normal bleeding time, thrombin time, PT
5
Q
What should you avoid if a patient has haemophilia?
A
- IM injections
- NSAIDS
6
Q
How do you manage a minor bleed with haemophilia a?
A
- Pressure and elevation of bleeding part
- Desmopressin to raise factor VIII levels
7
Q
How do you manage a major bleed with haemophilia a?
A
Give recombinant factor VIII
8
Q
What causes haemophilia B?
A
Factor IX deficiency
