Haemolytic Uraemic Syndrome (0) Flashcards
1
Q
When does HUS occur?
A
Occurs when thrombosis in small blood vessels throughout body
2
Q
What is HUS usually triggered by?
A
Shiga toxin
3
Q
Presentation of HUS?
A
Classic triad of
- Haemolytic anaemia
- AKI
- Low platelet count (thrombocytopenia)
4
Q
Cause of HUS?
A
- E. coli toxin called shiga toxin
- Loperamide increases risk of HUS
5
Q
Presentation of HUS?
A
-E. coli causes brief GI with bloody diarrhoea THEN 5 days after diarrhoea -Reduced urine output -Abdo pain -Lethargy and irritability -Confusion -HT -Bruising
6
Q
Management of HUS?
A
-Medical emergency
Condition is self limiting and supportive management = mainstay
- Anti-hypertensives
- Blood transfusions
- Dialysis
