Glomerulonephritis Flashcards
Definition of nephritis?
Genetic term that means inflammation of kidneys, not diagnosis or syndrome that has criteria
Nephritic syndrome definition?
-Group of symptoms not a diagnosis
Features of nephritic syndrome?
- Haematuria
- Oliguria
- Proteinuria
- Fluid retention
Nephrotic syndrome definition?
Refers to group of symptoms without specific underlying cause
Not a disease but way of saying symptoms
What is glomerulonephritis?
Umbrella term applies to condition that causes inflammation of or around glomerulus
Types of glomerular nephritis?
- Minimal change disease
- Focal segmental glomerulosclerosis
- Membranous glomerulonephritis
- IgA nephropathy ]-Post streptococcal glomerulonephritis
- Mesangiocapillary glomerulonephritis
- Rapidly progressive glomerulonephritis
- Good pasture syndrome
IgA nephropathy AKA?
Mesangioproliferative glomerulonephritis
Mesangiocapillary glomerulonephritis AKA?
Membranoproliferative
Treatment of most types of glomerulonephritis?
- Immunosuppression (roids)
- BP control by ACEis or ARBs
Presnetation of nephrotic syndrome?
Usually oedema
Possible frothy urine
Predisposes to thrombosis, HT, high cholesterol
Causes of nephrotic syndrome?
Idiopathic
-In adults usually focal segmental glomerulosclerosis
IgA nephropathy cause?
- Primary glomerulonephritis
- peak = age 20s
- Histology shows IgA deposits and glomerular mesangial proliferation
Membranous glomerulonephritis is most common type of nephritis?
True
Peaks at age 20s, and 60s
Causes of membranous glomerulonephritis?
Malignancy, Rheumatoid disorders and drugs (NSAIDs)
OR
Many are idiopathic
What does post-streptococcal glomerulonephritis present as?
1-3 weeks after streptococcal infection
Develop nephritic syndrome
Usually full recovery
Typically under 30 years old
