Haemoltyics

Question 1

Causes of anaemia

Answer 1

Bone marrow suppression
Destruction of rbc
Decreased formation of rbc
Increased destruction of rbc

Question 2

Total body iron content

Answer 2

2-5 g

Question 3

Site of iron absorption

Answer 3

Duodenum and jejunum

Question 4

Apoferritin

Answer 4

Iron binding protein

Question 5

Transferrin

Answer 5

A betaglobulin Transfer

Question 6

Ferrous sulfate preparation

Answer 6

•1.Ferrous sulphate: –contains 20%(hydrated salt-325mg-tab) and
32% ( dried salt-200mg tab) elemental iron.
It is the oldest & cheapest preparation.

Question 7

Ferrous gluconate

Answer 7

2.Ferrous gluconate: contains 12% elemental iron & is less gastric irritant-325 mg tab.
•3.Ferrous fumerate: contains 33% elemental iron

Question 8

Adverse effect of oral iron

Answer 8

•nausea,vomiting ,epigastric discomfort,
•dyspepsia, metallic taste,
constipation / diarrhoea &

•staining of teeth(mainly with liquid preparations).

Question 9

Inferon is known as

Answer 9

Iron dextran complex

Question 10

Jectofer

Answer 10

Iron sorbitol citric acid complex (Jectofer

Question 11

What is the recommended dose of jectoper and inferon

Answer 11

100mg

Question 12

To prevent the staining of the skin what technique is done

Answer 12

Z track technique

Question 13

Which drug is intramuscular lay only?

Answer 13

Iron sucrose complex

Question 14

Indications for parental iron therapy

Answer 14

• 1.Intolerance to oral iron.
• 2. Severe malabsorption.
• 3. Non compliance to oral iron.
• 4.Severe anaemia in the late stages of pregnancy.
• 5.Along with erythropoietin in patients with renal disease.