Haematology

Question 1

Kolionychia is a sign of which type of anaemia?

Answer 1

iron deficiency anaemia

Question 2

Patien tpresents with glossitis, which type of anaemia does this indicate?

Answer 2

B12/Folate deficiency anaemia

Question 3

What is the commonest cause of microcytic anaemia?

Answer 3

Iron deficiency

Question 4

What is the commonest cause of macrocytic anaemia?

Answer 4

Vit B12/ Folate deficiency

Question 5

Multiple myeloma is proliferation of what type of cells in bone marrow?

Answer 5

B cells, these proliferate into plasma cells

Question 6

Which clotting factors are deficient in haemophilia A / B?

Answer 6

A= VIII
B= IX

Question 7

Patient presents with swelling in their knee joint which you suspect to be caused by bleeding into the joint, Which condiiton may they have?

Answer 7

Haemophilia A / B

Question 8

What is the inheritance of haemophilia and what is the implication of this?

Answer 8

X-linked recessive

Majority of patient are male

Question 9

What is the management of haemophilia?

Answer 9

IV infusion of coagulation factor which is deficient
Desmopressin (stimulates release of von-willebrand factor)
Anti-fibrinolytics e.g tranexamic acid

Question 10

What are the 2 types of thrombosis? Composition? Complication?
Managment?

Answer 10

Arterial (platelet rich)- MI/Stroke
Antiplatelet

Venous (fibrin rich)- DVT / PE
Anticoagulant