haematology

Question 1

INR

Answer 1

5-8 with bleeding - ED for IV vit K then restart once INR <5

5-8 with no bleeding - omit 1-2 doses of warfarin and subsequent maintenance

Question 2

malignancies that cause high Plt (thrombocytosis)

Answer 2

lung
endometrial
gastro
colorectal
ovarian
renal

Question 3

CML (chronic myeloid leukaemia)

Answer 3

complication is hyperviscosity syndrome - headaches, deafness and visual changes - refer to on call haem

Question 4

Lymphoma

Answer 4

75% have lymphadenopathy
25% have B sx such as weight loss, fatigue, pruiritis and night sweats

Ix normocytic anaemia + raised eosinophils
Dx by lymph node biopsy reed Sternberg cells seen