Haematology Flashcards
class 1 of blood loss
0-15% lost
HR < 100
BP normal
cap refill normal
class 2 of blood loss
15-30% lost
tachycardic
BP normal
cap refill >2 sec
class 3 of blood loss
30-40% lost
tachycardic
BP reduced
cap refill > 2 sec
class 4 of blood loss
> 40% lost
really tachycardic
BP reduced
cap refill undetectable
anuric
what does cryoprecipitate contain?
factor 8 and fibrinogen
inherited haemolytic anaemia
defect in red cell
e.g. G6PDD, SCD, HS
acquired haemolytic anaemia
defects in environment of RBC
immune mediated or non-immune mediated
immune mediated haemolytic anaemia
warm AIHA = lymphoma, drug allergy, SLE
cold AIHE = M pneumonia, EBV, CMV
non-immune mediated haemolytic anaemia
infection
PNH
MAHA
TLS and calcium
hypocalcaemia
what happens in heparin induced thrombocytopaenia?
AB against complexes of platelet factor 4 and heparin
findings in HIT and management
low plt but prothrombotic state
switch to direct thrombin inhibitor
acute transfusion reactions (<24 hours)
acute haemolytic (ABO)
allergic/anaphylactic
infection (bacterial)
febrile non-haemolytic
respiratory (TACO, TRALI)
delayed transfusion reactions (>24 hours)
delayed type haemolytic transfusion reactions
infection (viral, malaria)
TA-GvHD
post transfusion purpura
Iron overload
what does bleeding time test?
platelets
