Haematinics Flashcards
What causes increased iron absorption?
Fe2+
haem iron
acids
ascorbate
solubilising agents
pregnancy
increased erythropoiesis
haemochromatosis
What causes decreased iron absorption?
Fe3+
non-organic iron
alkalis
phytates and phosphates
tea
tetracyclines
infections
high iron diet
high body iron stores
Iron deficiency anaemia blood results
low MCV
low serum iron
increased TIBC
low ferritin
Iron deficiency causes
inadequate diet
increased requirements
malabsorption
blood loss
When should GI investigations be done in iron deficiency anaemia?
all men
all post-menopausal women
symptomatic women
women >45
GI causes of iron deficiency anaemia
hookworm infections
oesophagogastric cancer
coeliac disease
crohn’s disease
gastritis
peptic ulceration
oesophagitis
gastrectomy
NSAID enteritis
Causes of folate deficiency
diet
increased utilisation
pathological
malabsorption
urinary loss
drugs
Causes of B12 deficiency
diet
gastric disease
ileal disease
infections
pancreatic disease
B12 destruction
Transcobalamin-2 deficiency
Autoantibodies present in pernicious anaemia
anti-parietal cell
anti-intrinsic factor
