Haem Differences Flashcards
Key feature of ALL
CNS infiltration (headache, CN palsies)
Specific ALL treatment
Methotrexate
Who gets ALL
Children, adults >45
AML sign
Gum hypertrophy
AML diagnostic feature
Auer rods
AML epidemiology
Elderly
CLL diagnostic feature
Smudge cells
CLL treatment
Watch and wait for mild. Rituximab
CLL epidemiology
Most common leukaemia in adults
CML features
Philadelphia chromosome (9&22 -> abnormal BCR-ABL). Gout
CML treatment
Tyrosine kinase inhibitors (imatinib)
Hodgkin lymphoma features
Lymphadenopathy painful on drinking alcohol. B symptoms
Hodgkin lymphoma diagnosis
Reed Sternberg Cells
Hodgkin lymphoma treatment
ABVD chemo
Hodgkin lymphoma epidemiology
Bimodal: early 20s & 70s
Non Hodgkin lymphoma features
Painless lymphadenopathy. B symptoms
Non Hodgkin lymphoma diagnosis
No Reed sternberg crlls
Non Hodgkin lymphoma treatment
RCHOP chemo
Non Hodgkin lymphoma epidemiology
Over 40s
Multiple myeloma features
CRAB
Multiple myeloma diagnosis
Bence Jones proteins in urine
Multiple myeloma treatment
VCD, VTD, MTP
Polycythaemia Vera features
JAK 2 mutation
G6PD deficiency diagnosis
Heinz bodies
