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2a > Haem Differences > Flashcards

Haem Differences Flashcards

1
Q

Key feature of ALL

A

CNS infiltration (headache, CN palsies)

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2
Q

Specific ALL treatment

A

Methotrexate

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3
Q

Who gets ALL

A

Children, adults >45

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4
Q

AML sign

A

Gum hypertrophy

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5
Q

AML diagnostic feature

A

Auer rods

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6
Q

AML epidemiology

A

Elderly

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7
Q

CLL diagnostic feature

A

Smudge cells

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8
Q

CLL treatment

A

Watch and wait for mild. Rituximab

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9
Q

CLL epidemiology

A

Most common leukaemia in adults

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10
Q

CML features

A

Philadelphia chromosome (9&22 -> abnormal BCR-ABL). Gout

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11
Q

CML treatment

A

Tyrosine kinase inhibitors (imatinib)

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12
Q

Hodgkin lymphoma features

A

Lymphadenopathy painful on drinking alcohol. B symptoms

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13
Q

Hodgkin lymphoma diagnosis

A

Reed Sternberg Cells

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14
Q

Hodgkin lymphoma treatment

A

ABVD chemo

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15
Q

Hodgkin lymphoma epidemiology

A

Bimodal: early 20s & 70s

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16
Q

Non Hodgkin lymphoma features

A

Painless lymphadenopathy. B symptoms

17
Q

Non Hodgkin lymphoma diagnosis

A

No Reed sternberg crlls

18
Q

Non Hodgkin lymphoma treatment

A

RCHOP chemo

19
Q

Non Hodgkin lymphoma epidemiology

A

Over 40s

20
Q

Multiple myeloma features

A

CRAB

21
Q

Multiple myeloma diagnosis

A

Bence Jones proteins in urine

22
Q

Multiple myeloma treatment

A

VCD, VTD, MTP

23
Q

Polycythaemia Vera features

A

JAK 2 mutation

24
Q

G6PD deficiency diagnosis

A

Heinz bodies

25
Q

Essential thrombocythemia features

A

50% JAK 2

26
Q

CML prognosis

A

Get treatment free remission in a high percentage following imatinib

27
Q

Myeloma blood film

A

Rouleaux formation (aggregations of rbcs)

28
Q

What leukaemia is Down syndrome most commonly associated with

A

AML

29
Q

What is MDS

A

Precursor to AML

2a (10 decks)

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