Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

2a > Endocrine > Flashcards

Endocrine Flashcards

1
Q

Water soluble hormones

A

Peptides (LH, FSH, insulin, prolactin,GH)

Amines (nAd, Ad, dopamine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fat soluble hormones

A

Thyroid hormone, cholesterol derivatives & steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cytoplasm receptor

A

Glucocorticoids, mineralocorticoird, androgens, progesterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Nuclear receptors

A

Oestrogen, thyroid hormone, vitamin d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Posterior pituitary

A

ADH, oxytocin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Gut peptides in appetite regulation

A

Grehlin pyy glp1, ckk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Increase food intake

A

NPY

AgRP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Decrease food intake

A

POMC -> alpha MSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Peptide YY

A

secreted but neuroendocrine cells in ileum, pancreas, colon. Binds to NPY & AgRP receptors - decreasing their secretion - inhibits gastric motility & reduces appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does CCK do

A

Stops eating. Delays gastric emptying, stimulates gall bladder contraction and insulin release. Causes satiety via vagus nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

POMC

A

Signals satiety

Needed for ACTH production. Without POMC get pale skin, adrenal insufficiency, hyperphagia and obesity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Low calcium

A

Long QT, paraesthesia, muscle spasm, seizures, cataracts, anxiety, dermatitis, impetigo herpetiformis, Chovstek & trousseau

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Dopamine agonists

A

Cabergoline
Brompcriptine
Quinagolide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Growth hormone producing tumour treatment

A

Cabergoline (has some effect on reducing GH levels)
Somatostatin anologues - more effective than cabergoline
Growth hormone receptor antagonists
Radiotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ADH receptor blocker

A

Tolvaptan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hyperthyroidism treatment

A

Anti thyroid drugs (carbimazole) - serious se: agranulocytosis
Radioactive iodine
Surgery

17
Q

Autoantibodies tested for in T1DM

A

Anti GAD, pancreatic islet cell Ab, Isley antigen 2 Ab, ZnT8

18
Q

Hypoglycaemia symptoms

A

Adrenaline -> anxiety hunger shaking sweating dizziness impaired vision weakness fatigue headache irritable fast heart beat, metallic taste in mouth

19
Q

DKA definition

A

Hyperglycaemia + raised plasma ketones + metabolic acidosis

20
Q

Metformin

A

Increased insulin sensitivity

SE nausea diarrhoea abdominal pain

21
Q

Sulfonylureas

A

E.g. gliclazide
Stimulates insulin release
SE: weight gain, hypo

22
Q

Thiazolinediones

A

Promote glucose uptake and utilisation and lipid metabolism and improve insulin sensitivity

23
Q

GLP1 analogues

A

Mimic GLP1 actions

24
Q

SGLT2 inhibitors

A

Remove excess glucose load (insulin dependent) reduce glucose reabsoeption at kidney causing glycosuria

25
Q

Other hormones that increase insulin resistance

A

GH, cortisol

2a (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions