gyn1 Flashcards
what is stress incontinence?
occurs in patients with weak urethral sphincter.
anything that increases abdo pressure - coughing, laughing, causes leakage of urine
give 2 non-pharma treatments of stress incontience?
- lifestyle changes - weight loss, smoking, caffeine, avoid straining
- pelvic floor exercises (physio)
(duloxetine can be used alongside physio)
how do pelvic floor exercises work?
pelvic floor muscle contraction -> urethral compression -> increased urethral pressure -> reduced leakage
what surgical options for stress incontinence?
sling
suspension - restores pressure to the urethra and supports urethra
what causes overactive bladder?
involuntary contractions of detrusor muscle -> urgency
3 symptoms of Oab
Urgency
frequency
nocturia
key in door urgency
epithelium of detrusor?
smooth muscle with transitional epithelium
innervation of detrusor?
sacral parasympathetic innervation
investigations for incontinence?
bladder diary
urinalysis
residual urine measuremen
ePAQ questionnaire
what info is obtained from bladder diary?
freq
quantity
fluid intake
diurnal variation
non pharma treatments of oab?
lifestyle changes
bladder drill
pads
what drugs are used for oab
oxybutynin
mirabegron
botox
how does oxybutynin work
Anticholinergic - M2/3 receptor antagonist. reduces detrusor innervation
what are side effects of oxybutynin
- dry mouth
- constipation
- blurred vision
- cognitive impairments
how does mirabegron work?
beta 3 agonist. relaxes detrusor and increases capacity of bladder