GU- Enuresis Flashcards

1
Q

vol or invol urination into clothes at the age when toilet training should be complete

A

“enuresis” per text

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2
Q

incontinence durine sleep

A

nocturnal enuresis

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3
Q

enuresis during waking hours

A

diurnal emuresis

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4
Q

night time wetting with no daytime concerns

A

monosymptomatic nocturnal emuresis

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5
Q

nocturnal enuresis plus some type of bowel or bladder dysfunction

A

non-monosymptomatic enuresis (NMNE)

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6
Q

enuresis in child who has never had urinary control

A

primary enuresis

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7
Q

enuresis in a child has previously been dry 6-12 months then begins wetting

A

secondary enuresis

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8
Q

DSM-V diagnostic criteria

A

minimum age 5 years old

at least one episode per month for at least 3 months

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9
Q

ICCS infrequent enuresis

A

4 or less times per month

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10
Q

ICCS frequent enuresis

A

four of more times per week

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11
Q

causes of enuresis

A

has definitive cause, not due to bad behavior or attention seeking

familial disposition- many found to be due to constipation

developmental comorbidities- strong collelation with adhd

always consider trauma or abuse

constipation, neuro dev delay, small bladder. sleep disorders, stress/family disruption, polyurina, inappropriate toilet training

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12
Q

palpate abd for signs of fecal impaction

A

hard mass in LLQ

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13
Q

indication of full bladder

A

abd tenderness over suprapubic area midline

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14
Q

testing UA and diff dx

A

UA- should be normal, looking for organic causes enuresis such as UTI- most common cause

DM, sickle cell-increased intake = increase output

CRF- inablilty to concentrate urine

hypercalciurea, neurogenic bladder, obstr uropathy, vaginitis, sleep apnea

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15
Q

differential dx pollakiuria

A

self limiting and benign

“daytime extraordinary urinary frequency”

8-12 times day, often as Q15-30 min

doesnt respond to meds, typically lasts 6 months but can last years

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16
Q

treatment should focus on daytime issue first if present then focus on night time

A
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17
Q

Treatment - urotherapy

A

non pharmocologic therapy

not as effective as alarm therapy and meds- good starting point

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18
Q

urotherapy education

A

Education-how bladder works, minimize embarassment/scolding, reinforce positives and childs wanting to be dry

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19
Q

urotherapy - bladder training

A

bladder training-void Q2hrs during day, awakning and prior to bed, proper sitting and emptying

20
Q

urotherapy diet and fluids

A

adequate water between bfast and lunch to avoid evening thirst- eliminate carb beverages, citus juices and caff

no dairy 4 hours before bedtime

no fluids 2 hours before bedtime

NEVER takes prescidence over adequate hyrdration

21
Q

urotherapy - monitor progress and manage constipation

A

keep voiding diary

manage constipation issues

22
Q

How long should we try urotherapy before medication and enuresis alarm?

A

3 months

use of alarms and desmopressin are also first line treatment, choice of urotherapy vs alarm/meds is up to family

23
Q

how do alarms reduce nocturnal enuresis?

A

increasing nocturnal bladder capacity or by enhanced arousal

does not reduce nocturnal output

24
Q

how is alarm worn and when to follow up and d/c

A

worn with undrpants, parents should awaken child if he/she doesnt awake

nightly for2-4 (3) months and until after patient is dry for at least 1 month (14 days min)

follow up is biweekly or monthly

25
Drug therapy for monosymptomatic nocturnal enuresis -first, second and third
desmopressin acetate (DDAVP)-first line imipramine (tofranil) - only thrid line therpy at tertiary care facilities- third line
26
desmopressin dose
0.2-0.4mg daily at bedtime 120mcg melt daily at bedtime up to 240 as equivalent dosage
27
desmopressin info- reduces nighttime urine production
effective in kids with nocturnal polyuria and normal bladder volume take on empty stomach, no caff/choc/nutrasweet/carb bev 30 min before bed then wake to void within 10hrs kids at least 6 years old do not use with nasal spray caution in HTN, CF (hyponatremia) any lyte imbalances use least amount effective can use daily or intermittantly d/c in 6 months to check for relapse, 80-100% will relapse with d/c
28
oxybutynin dose
anticholenergic - second line 5 mg once daily at bedtime, increase by 5mg MAX DOSE 20MG/DAY
29
oxybutynin notes
relaxes smooth mosclus of bladder to increase capacity, has antispasmotic and analgesic properties effective for daytime enuresis kids at least 5 years old
30
concerns for referral
weak or interrupted stream need to use abd pressure to urinate daytime incont and nocturnal enuresis combined
31
ectopic ureter results in
costant leakage
32
no response
less than 50% reduction in enuresis
33
partial response
50-99% reduction
34
complete response
100% reduction
35
relapse
more than one symptom relapse per month
36
continued success
no sympt at 6 months
37
complete success
no symptoms for 2 years
38
what age can treatment start?
6 years old
39
What do we do for 3-5 year olds?
benign neglect in the face of accidents for older children, more aggressive treatments are warranted, rarely indicates disease
40
Drug therapy for monosymptomatic nocturnal enuresis -second line
Anticholenergics oxybutynin (ditropan) Tolterodine (detrol)
41
Drug therapy for monosymptomatic nocturnal enuresis -third line
tricyclic antidepressant imipramine (tofranil) only thrid line therpy at tertiary care facilities- third line
42
Detrol notes
anticholinergic- second line treatment kids 12 and up
43
detrol dosage
44
anticholenergic s/e and warnings
detrol (tolterodine) and ditropan (oxybutynin) no not admin with fever, sweating is anticholinergic effect caution in kids who play vigerously, exericse, hot days s/e: dry mouth, blurred vision, facial flushing, CONSTIPATION, poor bladder emptying, mood changes
45
imipramine dose
46
46
imepramine notes
TCA- thrid line treatment has anticholenergis s/e as well as a CNS stimulant allows children to awaken to sensation of full bladder use with caution can cause seizures or cardiac arrythimas with OD