Gram Positive Rods

Question 0

Aerobic non motile, reheated fried rice/Chinese fried rice

Answer 0

Bacillus cereus

Question 1

Aerobic, non motile

Box car shaped/Medusa head

Answer 1

Bacillus anthracis

Question 2

Anaerobic, tennis racket like/lollipop like causing spastic paralysis

Answer 2

Clostridium tetani

Question 3

Anaerobic, bulging cans causing flaccid paralysis

Answer 3

Clostridium tetani

Question 4

Anaerobic, lecithinase gas forming

Answer 4

Clostridium perfringens

Question 5

Anaerobic causing pseudomembranes and antibiotic associated diarrhea

Answer 5

Clostridium defficile

Question 6

Aerobic, non motile, curved, chinese character

Answer 6

Corynebacterium diphtheriae

Question 7

Bacteria causing pseudomembranous pharyngitis

Answer 7

Corynebacterium diphtheria

Question 8

Aerobic, curved, tumbling motility with actin rockets

Answer 8

Listeria monocytogenes

Question 9

Spore forming gram positive rods

Answer 9

Clostridium

Bacillus

Question 10

Inhalation of spore from animal hair and wool

Answer 10

Woolsorters disease

B anthracis

Question 11

Dry gound glass surface and irregular edges with projections along lines of inoculation

Answer 11

Medusa head morphology

B anthracis

Question 12

DOC for Anthrax

Answer 12

Ciprofloxacin

Question 13

MCC of death in Anthrax

Answer 13

Pulmonarry hemorrhage

Question 14

Diseases with Pulmonary hemorrhage as their cause of death

Answer 14

Inhalational Anthrax
Congenital Syphilis
Weils syndrome
I Ate Cake SWeet

Question 15

A protease that cleaves proteins involved in the release of glycine from Renshaw cells in spinal cord

Answer 15

Tetanospasmin (Tetanus toxin)

Question 16

DOC for C tetani

Answer 16

Metronidazole

Question 17

A drug that inhibits glycine activity hence should not be used in C tetani

Answer 17

Penicillin

Question 18

This blocks acetylcholine release causing flaccid paralysis (descending pattern)

Answer 18

Botulinum toxin

Question 19

Triad of Botulism

Answer 19

Symmetric descending flaccid paralysis with prominent bulbar involvement (bulbar signs-diplopia, dysphonia, dysarthria, dysphagia)
Absence of fever
Intact sensorium

Question 20

Infant botulism

Answer 20

Floppy baby syndrome

Question 21

In infant botulism, theres absence of

Answer 21

Competitive bowel microbes

Question 22

Double hemolysis on blood agar

Answer 22

Clostridium perfringens

Question 23

A lecithinase that cleaves cell membrane

Answer 23

Alpha toxin

C perfringens causing gas gangrene

Question 24

DOC for gas gangrene

Answer 24

Penicillin

Question 25

Antibiotics that cause C defficile associated diarrhea

Answer 25

Clindamycin 1st and 2nd Gen Cephalosporins Ampicillin

Question 26

Sequelae of Pseudomembranous colitis

Answer 26

Toxic megacolon

Question 27

What causes Pseudomembranous pharyngitis?

Answer 27

Corynebacterium diphtheriae

Question 28

What causes Pseudomembranous esophagitis?

Answer 28

Candida albicans

Question 29

What causes Pseudomembranous colitis?

Answer 29

Clostridum defficile

Question 30

DOC for C defficile

Answer 30

Metronidazole | Vancomycin - poor oral bioavailability - stays at GI

Question 31

Club or comma shaped rods arranged in V ir L shape looks like a Chinese Character

Answer 31

Corynebacterium diphtheriae

Question 32

The toxigenicity of Corynebacterium diphtheriae is detected using

Answer 32

Modified Elek test

Question 33

Granules seen in Corynebacterium diphtheriae

Answer 33

Metachromatic granules/ Babes Ernst/ Volutin

Question 34

Pathogenesis of Diphteria

Answer 34

ADP ribosylation - exotoxin Beta prophage - encoded the exotoxin - transduction - lysogenized Corynebacterium Diphtheriae Elongation factor 2 - for translation Granules - metachromatic/ babes ernst/ volutin

Question 35

Beta prophage encoded toxins

Answer 35

``` ShigA like yoxin in EHEC Botulinum toxin Cholera toxin Diphtheria toxin Erythrogenic toxin in S pyogenes - Scarlet fever ```

Question 36

This results from death of mucosal epithelial cells

Answer 36

Psedomembrane

Question 37

Treatment for Corynebacterium diphtheriae

Answer 37

Antitoxin and Pen G

Question 38

Cold enhancement - paradoxical growth in cold temperature

Answer 38

Listeria monocytogenes

Question 39

Tumbling motility

Answer 39

Listeria monocytogenes

Question 40

Narrow zone of beta hemolysis

Answer 40

Listeria monocytogenes

Question 41

Ingestion of unpasteurized milk

Answer 41

Listeria monocytogenes (also get TB)

Question 42

This propels Listeria monocytogenes through the membrane of one human cell to another

Answer 42

Actin rockets

Question 43

Escape from phagosomes

Answer 43

Listeriolysin | Listeria monocytogenes

Question 44

DOC for Listeriosis

Answer 44

Ampicillin with or without Gentamicin