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Microbiology > Gram Positive Rods > Flashcards

Gram Positive Rods Flashcards

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Biology 101 flashcards
0
Q

Aerobic non motile, reheated fried rice/Chinese fried rice

A

Bacillus cereus

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1
Q

Aerobic, non motile

Box car shaped/Medusa head

A

Bacillus anthracis

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2
Q

Anaerobic, tennis racket like/lollipop like causing spastic paralysis

A

Clostridium tetani

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3
Q

Anaerobic, bulging cans causing flaccid paralysis

A

Clostridium tetani

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4
Q

Anaerobic, lecithinase gas forming

A

Clostridium perfringens

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5
Q

Anaerobic causing pseudomembranes and antibiotic associated diarrhea

A

Clostridium defficile

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6
Q

Aerobic, non motile, curved, chinese character

A

Corynebacterium diphtheriae

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7
Q

Bacteria causing pseudomembranous pharyngitis

A

Corynebacterium diphtheria

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8
Q

Aerobic, curved, tumbling motility with actin rockets

A

Listeria monocytogenes

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9
Q

Spore forming gram positive rods

A

Clostridium

Bacillus

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10
Q

Inhalation of spore from animal hair and wool

A

Woolsorters disease

B anthracis

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11
Q

Dry gound glass surface and irregular edges with projections along lines of inoculation

A

Medusa head morphology

B anthracis

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12
Q

DOC for Anthrax

A

Ciprofloxacin

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13
Q

MCC of death in Anthrax

A

Pulmonarry hemorrhage

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14
Q

Diseases with Pulmonary hemorrhage as their cause of death

A

Inhalational Anthrax
Congenital Syphilis
Weils syndrome
I Ate Cake SWeet

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15
Q

A protease that cleaves proteins involved in the release of glycine from Renshaw cells in spinal cord

A

Tetanospasmin (Tetanus toxin)

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16
Q

DOC for C tetani

A

Metronidazole

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17
Q

A drug that inhibits glycine activity hence should not be used in C tetani

A

Penicillin

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18
Q

This blocks acetylcholine release causing flaccid paralysis (descending pattern)

A

Botulinum toxin

19
Q

Triad of Botulism

A

Symmetric descending flaccid paralysis with prominent bulbar involvement (bulbar signs-diplopia, dysphonia, dysarthria, dysphagia)
Absence of fever
Intact sensorium

20
Q

Infant botulism

A

Floppy baby syndrome

21
Q

In infant botulism, theres absence of

A

Competitive bowel microbes

22
Q

Double hemolysis on blood agar

A

Clostridium perfringens

23
Q

A lecithinase that cleaves cell membrane

A

Alpha toxin

C perfringens causing gas gangrene

24
Q

DOC for gas gangrene

A

Penicillin

25
Q

Antibiotics that cause C defficile associated diarrhea

A

Clindamycin
1st and 2nd Gen Cephalosporins
Ampicillin

26
Q

Sequelae of Pseudomembranous colitis

A

Toxic megacolon

27
Q

What causes Pseudomembranous pharyngitis?

A

Corynebacterium diphtheriae

28
Q

What causes Pseudomembranous esophagitis?

A

Candida albicans

29
Q

What causes Pseudomembranous colitis?

A

Clostridum defficile

30
Q

DOC for C defficile

A

Metronidazole

Vancomycin - poor oral bioavailability - stays at GI

31
Q

Club or comma shaped rods arranged in V ir L shape looks like a Chinese Character

A

Corynebacterium diphtheriae

32
Q

The toxigenicity of Corynebacterium diphtheriae is detected using

A

Modified Elek test

33
Q

Granules seen in Corynebacterium diphtheriae

A

Metachromatic granules/ Babes Ernst/ Volutin

34
Q

Pathogenesis of Diphteria

A

ADP ribosylation - exotoxin
Beta prophage - encoded the exotoxin - transduction - lysogenized
Corynebacterium
Diphtheriae
Elongation factor 2 - for translation
Granules - metachromatic/ babes ernst/ volutin

35
Q

Beta prophage encoded toxins

A 
ShigA like yoxin in EHEC
Botulinum toxin
Cholera toxin
Diphtheria toxin
Erythrogenic toxin in S pyogenes - Scarlet fever
36
Q

This results from death of mucosal epithelial cells

A

Psedomembrane

37
Q

Treatment for Corynebacterium diphtheriae

A

Antitoxin and Pen G

38
Q

Cold enhancement - paradoxical growth in cold temperature

A

Listeria monocytogenes

39
Q

Tumbling motility

A

Listeria monocytogenes

40
Q

Narrow zone of beta hemolysis

A

Listeria monocytogenes

41
Q

Ingestion of unpasteurized milk

A

Listeria monocytogenes (also get TB)

42
Q

This propels Listeria monocytogenes through the membrane of one human cell to another

A

Actin rockets

43
Q

Escape from phagosomes

A

Listeriolysin

Listeria monocytogenes

44
Q

DOC for Listeriosis

A

Ampicillin with or without Gentamicin

Microbiology (10 decks)

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