GPP Pharmacology Flashcards

1
Q

Direct Acting Cholinergic Agonists

A
  • Carbachol
  • Pilocarpine
  • Bethanechol
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2
Q

Reversible Indirect Actinf Cholinergic agonists

A

DoRiPPEN
- Donepezil
- Rivastigmine
- Physostigmine
- Pyridostigmine
- Edrophonium
- Neostigmine

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3
Q

Irreversible indirect acting cholinergic agonists

A
  • Parathion
  • Malathion
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4
Q

Nicotinic Receptor Agonists

A
  • Nicotine
  • Varenicline
  • Acetylcholine
  • Choline
  • Epibatidine
  • Lobeline
  • Cytisine
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5
Q

Synthetic nicotinic agonists

A
  • Dimethyl phenyl piperazinum
  • Tetramethyl ammonium
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6
Q

M1 Anticholinergic drugs

A

Piperazine
Telenzepine
Dicyclomine
Trihexyphenidyl (benhexol)

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7
Q

M2 Anticholinergic drugs

A

Tripitamine
Methoctramine

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8
Q

M3 anticholinergic drug

A

DOTS 4 H

Darifenacin
Oxybutynin
Tolterodine
SolIfenacin
4-DAMP
Hexahydrosiladefenidol

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9
Q

M4 antichokinergic

A

Himbacine

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10
Q

Non selective Muscarinic receptor antagonist

A

Atropine
Homatropine
Scopolamine (Hyosine)

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11
Q

Natural alkaloid Antimuscarinic drigs

A

Atropine
Hyosine

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12
Q

Semisynthetic mydriatics antimuscarinic drug

A

Homatropine

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13
Q

Semisynthetic antiasthmatic antimuscarinic drig

A

Ipratropium
Tiotropium bromide

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14
Q

Semisynthetic GI spasmolytics

A

Hyosine butyl bromide

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15
Q

Synthetic mydraitic drugs

A

Tropicamide
Cyclopentolate

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16
Q

Synthetic GI spasmolytics

A

DIG COP

Dicyclomine
Isopropamide
Glycopyrolate

Clidinium
Oxyphenonium
Pipenzolate

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17
Q

Synthetic antimuscarinic Anti ulcer drugs

A

Pirenzapine

Telenzepine

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18
Q

Synthetic antimuscarinic vesico-selective drugs

A

SOFT blad-Dar

SolIfenacin
Oxybutynin
Fesoterodine
Flavoxate
Tolteridine
Darifenacin

19
Q

Synthetic antimuscarinic antiparkinson’s

A
  • Benztropine
  • Biperiden
  • Benzhexol (trihexyphenidyl)?
20
Q

Competitive ganglion blockers

A

Hexamethinium
Pentolinum
Mecamlyamine
Pempidine
Trimethaphan

21
Q

Persistent depolarizing ganglion blockers

A

Nicotine
Anticholinesterases (low dose)?

22
Q

List the long acting NMJ non-depolarazing blockers

A
  • Pancuronium
  • d-Tubocurarine
  • Pipecuronium. Pipecuronium is largely excreted by the kidneys.
  • Doxacurium

PDPD

23
Q

List the intermediate acting NMJ depolrizing blockers

A
  • Vecuronium
  • Atracurium
  • Rocuronium
  • Cistracurium
  • Ropacuronium
24
Q

List the short acting NMJ depolarizing blockers

A

Mivacurium

25
Q

List the steroidal NMJ depolarizing blockers

A
  • Pancuronium
  • Vecuronium
  • Pipecuronium
  • Rocuronium
  • Rapacuronium
26
Q

List the benzylisoquinoline NMJ depolarizing blockers

A
  • d-Tubocurarine
  • Atracurium
  • Doxacuraium
  • Cisatracurium
  • Mivacurium
  • Metocurine
27
Q

List others non-specific NMJ depolarizing blockers

A
  • Gallamine
  • Alcuronium
28
Q

What is the prototype depolarizing blockers

A

Succinylcholine

29
Q

List the enzymes used in synthesis of E and NE

A
  • Tyrosine hydoxylase
  • Dopa decarboxylase
  • Dopamine B-hydroxylase
  • PNMT (Phenylethanolamine-N-Methyltransferase)
30
Q

List the non-selective agonists

A
  • Adrenaline
  • Noradrenaline
  • Isoprenalol
31
Q

List the alpha-1 agonists

A

XP TOMMMM

  • Xylometazoline
  • Phenylephrine
  • Tetrahydrozoline
  • Oxymetazoline
  • Methoxamine
  • Mephentermine
  • Metaraminol
  • Midodrine
32
Q

List the Alpha-2 agonists

A

GAG CAC BD
- Guanfacine
- Apraclonidine
- Guanabenz
- Clonidine
- Alpha-methyl dopa
- Clenbuterol
- Brimonidine
- Dexmedetomidine

33
Q

List the Beta-1 agonists

A

DDX
- Dobutamine
- Denopamine
- Xamoterol

34
Q

List the Beta-2 Agonists

A

FAP TIMSSS For Rito
- Fenoterol
- Albuterol
- Procaterol
- Terbutaline
- Isoetharine
- Metaproterenol
- Salmeterol
- Salbuterol
- Salbutamol
- Formoterol
- Ritodrine
- Bitolterol

35
Q

List the Beta-3 Agonists

A

VARMS
- Vibegron
- Amibegron
- Solabegron
- R040-2148
- Mirabegron

36
Q

List the Alpha-non selective antagonists

A

PPTE
- Phenoxybenzamine
- Phentolamine
- Tolazoline
- Ergol alkaloids

37
Q

List the Alpha-2 selective antagonists

A

YII
- Yohimbine
- Imiloxan
- Idazoxan

38
Q

List the Beta-non selective Antagonists

A

B CC PPP TLN
- Bucindolol
- Carteolol
- Carvedilol
- Penbutolol
- Pindolol
- Propanolol
- Timolol
- Labetalol
- Nadolo

39
Q

List the Beta-1 selective antagonists

A

Aaron Married Covenant Nation’s BABE lol
- Acebutolol
- Metoprolol
- Celiprolol
- Nebivolol
- Bisoprolol
- Atenolol
- Betaxolol

40
Q

List the beta-2 selective antagonists

A

BI
- Butoxamine
- ICI-118, 551

41
Q

List the examples of first generation Penicillin

A
42
Q
A
43
Q
A