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TimmyAbioye’s Pharmac > Antivirals > Flashcards

Antivirals Flashcards

1
Q

Classify the Non-Retroviral AV drugs

A

Viral DNA Polymerase Inhibitors
Viral Neuraminidase Inhibitors
Viral Coat Disassembly Inhibitors
NS3 protease inhibitors

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2
Q

List the Viral DNA Polymerase Inhibitors

A

Acyclovir
Famciclovir
Ganciclovir
Peniciclovir
Valacyclovir
Valganciclovir
Ribavirin
Cidofovir
Foscarnet
Idoxuridine

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3
Q

List the inhibitors of viral neuraminidase

A

Osetalmivir
Zanamivir
Laninamivir
Peramivir

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4
Q

List the inhibitors of viral coat disassembly

A

Amantadine
Rimantadine

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5
Q

List the NS3 protease inhibitors

A

Asunaprevir
Boceprevir
Grazoprevir
Paritaprevir
Simeprevir
Telaprevir

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6
Q

Classify the ARV drugs

A

Nucleoside/ Nucleotide Reverse Trabscriptase Inhibitors (NRTIs)

Non-nucleoside RTIs (NNRTIs)

Protease Inhibitors

Fusion Inhibitors

Entry/ CCR5 antagonists

Integrase Inhibitors

Maturation Inhibitors

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7
Q

List the NRTIs

A

Abacavir

Tenofovir (a nucleotide)

Didanosine

Emtricitabine

Zalcitabine

Lamivudine

Stavudine

Zidovudine

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8
Q

List the first generation NNRTIs

A

END

Efavirenz

Nevirapine

Delavirdine

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9
Q

List the second generation NNRTIs

A

DER

Daravirine

Etravirine

Rilpivirine

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10
Q

List the HIV protease Inhibitors

A

Amprenavir

Droxinavir

Fosamprenavir

Indinavir

Lopinavir

Nelfinavir

Ritonavir

Saquinavir

Telinavir

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11
Q

List the inhibited of HIV fusion

A

Enfuvurtide

Ibalizumab

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12
Q

List the first generation HIV integrase inhibitors

A

Raltegravir

Elvitegravir

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13
Q

List the second generation HIV integrase inhibitors

A

Dolutegravir

Bictegravir

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14
Q

List the Entry Inhibitors or CCR5 antagonists

A

Maraviroc

Aplaviroc

Vicriviroc

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15
Q

List the maturation inhibitors

A

Vivecon

Bevirimat

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16
Q

What is the guideline for HAART

A

Tenofovir + emtricitabine + efavirenz

Tenofovir/emtricitabine + atazanavir/ritonavir

Tenofovir/emtricitabine + darunavir/ritonavir

Tenofovir/emtricitabine + raltegravir

Tenofovir/emtricitabine + Elvitegravir/cobicistat

Tenofovir/emtricitabine + Dolutegravir

Abacavir/ Lamivudine + Dolutegravir in HLA B negative

Note that Lamivudine can replace emtricitabine in all the regimen

17
Q

Recommendation for Post exposure prophylaxis

A

Tenofovir/ Emtricitabine + Lopinavir/Ritonavir

Tenofovir/ Emtricitabine + Atazanavir/Ritonavir

Lamivudine can replace emtricitabine

TimmyAbioye’s Pharmac (8 decks)

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