CNS Pharmacology

Question 1

Group of drugs that can be used as anxiolytics

Answer 1

• Benzodiazepines (BZDs)
• Barbiturates (BARBs)
• 5HT1A receptor agonist
• 5HT2a, 5HT2c and 5-HT3 receptor antagonist

If ANS symptoms are present
- Beta antagonist
- Alpha- 2 agonist

Other drug include
- TCAs
- MAOIs
- Antihistaminic drugs
- Antipsychotics

Novel drugs include
- CCKb
- EAA’s/ NMDA

Question 2

What drug is used for OCD?

Answer 2

Tricyclic Antidepressants

Question 3

What drug is used for panic attacks?

Answer 3

MAOIs

Question 4

Classify sedatives/hypnotics

Answer 4

• Barbiturates
• Benzodiazepines
• Non benzodiazepine hypnotics
• Miscellanous drugs

Question 5

Classify Barbiturates and state the drugs under the classification

Answer 5

Long Acting
- Phenobarbitone

Short Acting
- Butobarbitone
- Pentobarbitone

Ultra-short acting
- Thiopentone
- Methohexitone

Question 6

What benzodiazepines can be used as hypnotics?

Answer 6

• Diazepam
• Flurazepam
• Nitrazepam
• Alprazolam
• Temazepam
• Triazolam

Question 7

What Benzodiazepines can be used as antianxiety?

Answer 7

• Diazepam
• Chlordiazepoxide
• Oxazepam
• Lorazepam
• Alprazolam

Question 8

What benzodiazepines can be used as anticonvulsant?

Answer 8

• Diazepam
• Lorazepam
• Clonazepam
• Clobazam

Question 9

List the Non BZD hypnotics

Answer 9

• Zolpidem
• Zaleplon
• Zolpiclone (Eszopliclone)
• Chloral hydrate

Question 10

List the Miscellaneous drugs used as sedatives/hypnotics

Answer 10

• Melatonin
• Ramelteon
• Antidepressants
• Antihistamines

Question 11

Classify antiepileptic drugs based on the chemical structure

Answer 11

• Hydantoin
• Iminostilbene
• Succinimide
• Benzodiazepines
• Aliphatic carboxylic acid
• Phenyltriazine
• Barbiturates
• Cyclic GABA analogue
• Deoxybarbiturate
• Newer drugs

Question 12

List Hydantoin in epilepsy

Answer 12

Phenytoin
Fosphenytoin

Question 13

List Iminostilbene in epilepsy

Answer 13

• Carbemazepine
• Oxcarbazepine

Question 14

What are the succinimide in epilepsy

Answer 14

Ethosuximide

Question 15

What are the benzodiazepines used in epilepsy

Answer 15

• Clonazepam
• Diazepam
• Lorazepam

Question 16

List the aliphatic carboxylic acid

Answer 16

• Valproic acid
• Sodium valproate
• Divalproex

Question 17

List the phenyltriazine in epilepsy

Answer 17

Lamotrigine

Question 18

List the barbiturates in epilepsy

Answer 18

Phenobarbitone

Question 19

List the cyclic GABA in epilepsy

Answer 19

Gabapentin

Question 20

List the newer drugs in epilepsy

Answer 20

• Vigabatrin
• Topiramate
• Tiagabine
• Zonisamide
• Levetiracetam

Question 21

List the First generation epileptic drugs

Answer 21

• Phenobarbitone
• Phenytoin
• Carbamazepine
• Valproate
• Ethosuximide

Question 22

List the second generation epileptic drugs

Answer 22

• Levetiracetam
• Lamotrigine
• Oxcarbazepine
• Gabapentin
• Zonisamide
• Pregabalin

Question 23

List the 3rd generation antiepileptic drugs

Answer 23

• Retigabine
• Bivaracetam
• Lacosamide
• Lasigamine
• Carabersat
• Carisbamate

Question 24

What are the 2 types of General anesthetics

Answer 24

Inhalational Anesthetics
Intravenous Anesthetics

Question 25

What are the types of inhalational anesthetics

Answer 25

• Nitrous Oxide
• Halogenated anesthetics
  
  • Halothane
  • Isoflurane
  • Sevoflurane
  • Enflurane

Question 26

What are the intravenous anesthetics

Answer 26

• Propofol
• Thiopental sodium
• Ketamine