Cardiovascular pharmacology Flashcards

1
Q

Class 1a Anti-arrhythmic drugs

A

Quinidine

Disopyramide

Procainamide

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2
Q

Class 1b anti arrhythmic drugs

A

Lidocaine

Phenytoin

Mexilitine

Tocainide

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3
Q

Class 1c anti arrhythmic drugs

A

Ecainide

Flecainide

Propafenone

Indecainide

Moricizine

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4
Q

Class II anti arrhythmic drugs

A

Beta non-selective blockers:
Timolol

Oxprenalol

Propranolol

Penbutalol

Pindolol

Sotalol

Carvedilol

Labetalol

Beta1 selective blockers
Acebutalol

Metoprolol

Bisiprolol

Atenolol

Betaxolol

Esmolol

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5
Q

Class III anti arrhythmic

A

ASIDE

Amiodarone

Sotalol

Ibutilide

Dofetilide

Dronedarone.

E-4031

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6
Q

Class IV anti arrhythmic drugs

A

Verapamil

Diltiazem

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7
Q

Class V anti arrhythmic drugs

A

MAD

Magnesium

Adenosine

Digoxin

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8
Q

List the classes of drugs used as anti hypertensives

A

Sympatholytic drugs

Calcium channel blockers

Angiotensin Converting Enzyme Inhibitors

Angiotensin II receptor Antagonist

Vasodilators

Diuretics

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9
Q

What are the classes of sympatholytic agents used as anti hypertensives

A

Beta blockers

Alpha blockers

Alpha 2 agonist

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10
Q

Beta blockers used as anti hypertensives

A

Beta non selective blockers:
Timolol

Oxprenalol

Penbutalol

Pindolol

Propranolol

Sotalol

Nadolol

Labetalol

Carvedilol

Beta 1 blockers:
Atenolol

Metoprolol

Nebivolol

Betaxolol

Acebutalol

Bisoprolol

Esmolol

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11
Q

Alpha blockers used as anti hypertensives

A

Alpha non selective blockers
Phentolamine

Phenoxybenzamine

Alpha 1 blockers
Prazosin

Indoramine

Doxazosin

Tamsulosin

Tolazosin

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12
Q

Mixed adrenergic antagonists used as anti hypertensives

A

Bucindolol

Carvediolol

Labetalol

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13
Q

Centrally acting agents used as anti hypertensives

A

These are Alpha 2 Receptor Agonists

Clonidine

Guanabenz

Guanfacine

Moxonidine

Methyl DOPA

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14
Q

Adrenergic neuron blockers

A

Reserpine

Guanadrel

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15
Q

What are the classes of calcium channel blockers used as Antihypertensives

A

Dihydropyridines

Non dihydropyridines

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16
Q

List the dihydropyridines

A

FILL CANNNN

Felodioine

Isradipine

Lercanidipine

Levamlodipine

Cilnidipine

Amlodipine

Nifedipine

Nicardipine

Nimodipine

Nitredipine

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17
Q

List the non dihydropyridines

A

Verapamil (Diphenyalkylamines)

Benzothiazepines (Diltiazem)

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18
Q

List the ACE Inhibitors

A

FLEB PQRCT

Fosinopril

Lisinopril

Enalapril

Benazepril

Perindopril

Quinapril

Ramipril

Captopril (prototype)

Trandolapril

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19
Q

List the Angiotensin II receptor antagonists

A

COT VILE

Candesartan

Olmesartan

Telmisartan

Valsartan

Irbesartan

Losartan

Eprosartan

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20
Q

Vasodilators used as Antihypertensives

A

Arterial vasodilators
Minoxidil

Diazoxide

Hydralazine

Venous vasodilators:
Sodium nitroprusside

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21
Q

List the classes of drugs used in hypercholesterolemia/dyslipidemia

A

Statin

Bile acid binding resins

Cholesterol absorption inhibitors

Fibrates

Niacins

PCSK9 inhibitors

Novel agents

22
Q

List the statins

A

Atorvastatin

Simvastatin

Lovastatin

Pravastatin

Rosuvastatin

Pitavastatin

Fluvastatin

23
Q

List the bile acid binding resins used in hypercholesterolemia

A

Cholesevelam

Colestipol

Cholestyramine

24
Q

List the cholesterol absorption inhibitors

A

Ezetimibe

Plant tenol esters

25
Q

List the fibrates

A

Fenofibrate

Bezafibrate

Clofibrate (obsolete)

Gemfibrozil

26
Q

List the niacin’s used in hypercholesterolemia

A

Niacin (nicotinic acid)

27
Q

PCSK9 inhibitors used in hypercholesterolemia

A

Alirocumab

Evolocumab

28
Q

PCSK9 inhibitors used in hypercholesterolemia

A

Alirocumab

Evolocumab

29
Q

Novel agents uses in hypercholesterolemia

A

Anacetrapib

30
Q

List the groups of drugs used as anticoagulants

A

Heparins

Vitamin K Antagonists

Direct Thrombin Inhibitors

31
Q

List the heparins

A

Unfractioned Heparin

Low Molecular Weight Heparin

Synthetic Pentasaccharides
- Fordaparinox
- Idraparinox

32
Q

List the Vitamin K Antagonists

A

Warfarin (Coumarin derivative)

Arisindione

Acenocoumarol, Phenprocoumon

33
Q

List the Direct Thrombin Inhibitors

A

Hirudin

Bivalirudin

Synthetic:
Argatroban

Dabigatran

Ximelagatran

34
Q

List the anti platelets

A

Aspirin

Clopidogrel

Abciximab

Dipyridamole

Predogrel

Tirofiban

35
Q

List the fibrinolytics

A

Eminase (Anistreplase)
Retavase (reteplase)
Streptase (streptokinase, Kabikinase)
t-PA (Activass)
TNKase (tenecteplase)
Abbokinase, Kinlytic (rokinase)

36
Q

List the antifibrinolytics

A

Aminocaproic acid

Aprotinin

Tianexamic acid

Vitamin K1

37
Q

Oral iron

A

Fesulf
Fergon

38
Q

Drugs that can interfere with iron absorption

A

Antacids
Colestyramine
Neomycin
Quinolones
Tetracyclines
Levodopa & Carbidopa
Levothyroxine

39
Q

Drug interactions with Folic acid

A

Phenytoin
Phenobarbitone
Cotrimoxazole & Trimethoprim
MMT (Magnesium Trisilicate)
Sulphasalazine

40
Q

Bone marrow stimulants

A

Filgrastim
Epoetin Alfa

41
Q

Myelosuppressive agents used to treat polycythemia

A

Interferon Alfa-2b
Anagrelide (affects platelet number)
Aspirin (affects platelet function)

42
Q

List the classes of drugs used in Malaria

A
  • Arylaminoalcohol
  • 4-aminoquinolines
  • 8-aminoquinolines
    -Sulphone
  • Biguanides
  • Antibiotics
  • Napthoquinolines
  • Peroxides
43
Q

List the Arylaminoalcohol

A

Quinoline
- Quinidine
- Mefloquine

Phenanthrene
- Halophanthrene
- Limenfantrine

44
Q

List the 4-aminoquinolines

A
  • Chloroquine
  • Amodiaquine
  • Piperaquine
  • Napthoquinoline
  • Mepacrine (acridine)
  • Pyronaridine (benzonaphthridine)
45
Q

List the 8-aminoquinolines

A
  • Primaquine
  • Pamaquine
46
Q

List the Sulphones used in malaria

A
  • Sulphonamides
    • Sulphadoxine
    • Sulphalene
    • Co-trimoxazole
  • Dapsone
47
Q

List the Biguindes

A
  • Proguanil
  • Chlorproguanil
  • Cycloguanil
  • Chlorcycloguanil
  • Pyrimethamine
48
Q

List the antibiotics used in malaria

A
  • Tetracyclines
  • Doxycline
  • Clindamycin
  • Fluoroquinolones
49
Q

List the Peroxides used in Malaria

A
  • Artemisinin
  • Arthemeter
  • Artemotil
  • Artesunate
  • Artelinic acid
  • Dihydroartemisin
50
Q

List the Artemisin based combinations in Malaria

A
  • Artemeter and lumefantrine (Co-artem)
  • Artesunate and sulfadoxine-pyrimethamine
  • Artesunate and Amodiaquine
  • Artesunate and mefloquine
51
Q

List the non-artemisin based combinations

A
  • Proguanil and Atovaquone (Malarone)
  • Dapsone and Pyrimetamine (Maloprim)
  • Dapsone and Chlorproguanil (LAPDAP)
  • Sulfalene-pyrimethamine
  • Mefloquine- sulfadoxine-pyrimethamine
52
Q
A