Cancer Chemotherapy

Question 1

What are the classes of drugs used as cancer chemotherapy

Answer 1

• Alkylating agents
• Antimetabolites
• Natural products
• Hormones and antagonists
• Miscellaneous drugs

Question 2

List the alkylating agents used in cancer chemotherapy

Answer 2

• Nitrogen Mustard
• Busulfan
• Ethylene imines
• Methylmalamines
• Methylhydrazine derivatives
• Alkyl sulfonate
• Nitrosoureas
• Triazenes (Temozolamide)
• Platinium co-ordination complexes
• ThioTEPA
• Treosulfan

Question 3

List the Nitrogen Mustards

Answer 3

• Cyclophosphamide
• Chlorambucin
• Ifosfamide
• Melphalam
• Estramustine
• Mechloroethamine

Question 4

What are examples of Nitrosoureas

Answer 4

Lomustine
Carmustine

Question 5

List the platinium co-ordination complexes

Answer 5

• Cisplastin
• Carboplatin
• Oxaliplatin
• Dacarbazine
• Temozolomide

Question 6

List the antimetabolites used in cancer

Answer 6

• Folic Acid analogues
• Pyrimidine analogues
• Purine analogue
• Others

Question 7

List the folic acid analogues

Answer 7

Methotrexate

Question 8

List the pyrimidine analogues

Answer 8

• Fluorouracil
• Raltitrexed
• Pemetrexed
• Capecitabine
• Cytarabine
• Gemcitabine

Question 9

List the purine analogues

Answer 9

• Fludarabine
• Pentostatin
• Cladribine
• Mercaptopurine
• Tioguanine

Question 10

List the natural products used in the cancer chemotherapy

Answer 10

• Vinca alkaloids: Vinblastine and Vincristine
• Taxanes
• Camptothecins
• Antibiotics

Question 11

List the hormones and antagonists used in cancer chemotherapy

Answer 11

• Estrogen
• Prosgestin
• Androgens
• Adrenocorticoids

Question 12

List miscellaneous

Answer 12

• Protein tyrosine kinase inhibitors
• Biological response modifiers