GP Week 2 Flashcards
Exam Prep
HAS-BLED: A tool for identifying risk factors for bleeding in patients with AF.
- H - Hypertension - Systolic > 160 mmHg.
- A - abnormal liver or renal function.
- S - stroke history
- B - bleeding history or predisposition to bleeding
- L - labile INRs
- E - elderly > 65 years
- D - drugs, antiplatelets, NSAIDs, or alcohol > 8 units per week
CHA2DS2-VASc: A tool to further risk stratify low-risk people with non-valvular AF.
- C - congestive heart failure/ LVF = 1
- H - hypertension = 1
- A - age > 75 years = 2
- D - diabetes mellitus = 1
- S - stroke or TIA history = 2
- V - vascular disease, prior MI, PAD, aortic plaque = 1
- A - age 65-74 years = 1
- Sc - sex category, female = 1
CHADS2: Stroke risk assessment in people with non-valvular AF.
- C - congestive heart failure history = 1
- H - hypertension, include controlled = 1
- A - age > 75 years = 1
- D - diabetes mellitus = 1
- S - stroke or TIA history = 2
Australian prescriber indications for Rivaroxaban.
- AF
2. VTE
Australian prescriber indications for Dabigatran.
- AF
Australian prescriber indications for Apixaban.
- AF
2. VTE
Australian prescriber indications for Warfarin.
- AF
- VTE
- Valvular heart disease
Concomitant medications that increase effects of anticoagulants.
- Amiodarone (Warfarin)
- Erythromycin (Apixaban and Rivaroxaban)
- Verapamil (Dabigitran)
Concomitant medications that decrease the effect of anticoagulants.
- Rifampicin (all)
Medication choice for management of hypertension in myocardial infarction patients and symptomatic patients with angina.
- ACEi with beta blocker or calcium channel blocker
Medication choice for management of hypertension in chronic heart failure patient.
- ACEi with beta blocker
2. ARB if ACEi not tolerated
Medication choice for management of hypertension in the patient with peripheral vascular disease.
- ACEi or ARB
Medication choice for management of hypertension in older patients.
- ACEi or ARB
Classifications of clinical blood pressure in adults.
- Optimal = < 120 / < 80
- Normal = 120-129 / 80-84
- High-normal = 130-139 / 85-89
- Grade 1 HTN = 140-159 / 90-99
- Grade 2 HTN = 160-179 / 100-109
6 Grade 3 HTN = >180 / > 110
Diagnosis of asthma in adults is based on:
- History
- Physical examination
- Considering other diagnosis
- documenting variable airflow limitations
9 Findings that increase the probability diagnoses of asthma in adults.
- Classic symptoms, chest tightness, wheeze, cough, breathlessness.
- Symptoms worse at night an early morning
- Symptoms recurrent or seasonal
- Obvious triggers, drugs or environmental
- Family history of asthma or atopic history
- Symptoms began in childhood
- Eosinophillia or raised blood IgE
- Rapidly relieved by SABA
- FEV1 or PEF lower than predicted
9 Findings that decrease the probability diagnosis of asthma in adults.
- Dizziness, light-headedness, peripheral tingling
- Isolated cough with no other respiratory symptoms.
- Chronic sputum production.
- No physical findings on chest examination.
- Change in voice
- Symptoms only occur with URTI
- Smoking history
- CVD
- Normal spirometry
Step wise approach to adjusting asthma medication in adults.
- All patients - PRN SABA
- Most patients - add ICS low dose
- Some patients - change to ICS/ LABA (low dose)
- Few patients - change to ICS/ LABA (high dose)
- Referral
Lipid lowering therapy if LDL is not responding to maxed out statins or those patients intolerant of statins.
- Ezetimibe
- Bile acid binding resin
- Nicotinic acid
Lipid lowering therapy for those patients with elevated triglycerides.
- Fenofibrate
- Nicotinic acid
- Fish oil
New York Heart Association function classifications in heart failure.
- Class I = asymptomatic
- Class II = symptoms with normal activity
- Class III = symptoms with less than normal activity
- Class IV = symptoms at rest
4 most common causes of heart failure.
- Ischaemic heart disease
- Hypertension
- Valvular heart disease
- Idiopathic dilated cardiomyopathy
Less common causes of heart failure.
- Diabetes
- Myocarditis
- Congenital heart disease
- Drug induced
Beta blockers for use in heart failure.
- Carvedilol
- Bisoprolol
- Nebivolol
- Extended release metoprolol
4 components of COPD management.
- Optimising function
- Preventing deterioration
- Developing support networks and self management skills
- Managing exacerbations
Classifications of COPD based on FEV1 post- bronchodilator spirometry.
- Mild = 60-80% predicted
- Moderate = 40-59% predicted
- Severe = < 40% predicted
Pharmacotherpay for mild COPD.
- Symptomatic SABA, SAMA, PRN
- LAMA if frequent deterioration
- Slow release oral theophylline if inhaler use not possible.
Pharmacotherapy for moderate and severe COPD.
- Symptomatic SABA, SAMA, PRN
- LABA if frequent deterioration
- LAMA - tiotropium once daily
- ICS - fluticasone if < 50% predicted
- Slow release oral theophylline if inhaler use not possible
8 Modifiable risk factors for CVD.
- Smoking
- Hypertension
- Diabetes
- Dyslipidaemia
- BMI, obesity
- Poor nutrition
- Sedentary lifestyle
- Excessive alcohol intake
4 non- modifiable risk factors for CVD.
- Age
- Sex
- Family history of premature CVD
- Social, cultural history.
6 Most commonly used medication types to AVOID in systolic heart failure (HFrEF).
- COX-2 selective NSAIDs
- Thia-zolidi-nediones
- Corticosteroids
- Anti-arrythmics
- Non-dihydropyridine calcium channel blockers
- TCAs
Non-drug therapy for COPD.
- Pulmonary rehabilitation with physiotherapist.
5 Barriers to quitting smoking.
- Weight gain
- Coping with stress
- Withdrawal from nicotine
- Fear of failure
- Peer or social pressure
Pharmacotherapy for smoking cessation.
- Nicotine replacement therapy
- Varenicline
- Bupropion