GP - MSK Flashcards
What does an x-ray show in patients with OA?
LOSS:
- Loss of joint space
- Osteophytes forming at joint margins
- Subchondral sclerosis
- Subchondral cysts
Which joints are usually affected in OA?
- Large weight-bearing joints (hip/knee)
- Carpometacarpal joints
- DIP/PIP joints
What are the clinical features of OA?
- Pain following activity - improves with rest
- Unilateral symptoms
- No systemic upset
What is the management for OA?
- Lifestyle changes = weight loss/muscle strengthening exercises/aerobic fitness
- Topical NSAIDs (first line)
- Oral NSAIDs + PPI
- Intra-articular steroid injections
- Joint replacement
What will an x-ray show in RA?
LOSE
- Loss of joint space
- Osteopenia
- Soft tissue swelling
- Erosions
What are the clinical features of gout?
- Maximal intensity develops within 12 hours
- Pain
- Swelling
- Erythema
- Often 1st MTP joint or ankle/wrist/knee
What are the investigations for gout?
- Bloods = uric acid levels (>360 umol/L)
- Synovial fluid analysis = needle shaped negatively birefringent monosodium urate crystals under polarised light
- X-ray = joint effusion/well-defined ‘punched-out’ erosions with sclerotic margins with overhanging edges/preservation of joint space
What is the management for gout?
- FIRST LINE = NSAIDs/colchicine (+PPI)
- Lifestyle changes = reduce alcohol/lose weight/avoid food high in purines
- Oral steroids e.g. prednisolone
- Intra-articular steroid injection
- Urate-lowering therapy (allopurinol/febuxostat)
What are the clinical features and investigations for pseudogout?
- Knee/wrist/shoulders most commonly affected
- Pain
- Swelling
- Erythema
- Joint aspiration = weakly-positive birefringent rhomboid-shaped crystals
- X-ray = chondrocalcinosis
What is the management for pseudogout?
- Aspiration of joint fluid (rule out septic arthritis)
- NSAIDs
- Intra-articular/intra-muscular/oral steroids
What are the clinical features of polymyalgia rheumatica?
- Typically >60 years
- Rapid onset (<1 month)
- Aching/morning stiffness in proximal limb muscles
- Polyarthralgia
- Lethargy/depression
- Low-grade fever/anorexia/night sweats
What are the investigations for polymyalgia rheumatica?
- Bloods = ESR raised
- CK and EMG normal
What is the management for polymyalgia rheumatica?
Prednisolone
What are red flags for lower back pain?
- Age <20 or >50 years
- History of previous malignancy
- Night pain
- History of trauma
- Systemically unwell
What are the clinical features of facet joint pain?
- May be acute or chronic
- Pain worse in morning and on standing
- Pain over facets
- Pain worse on extension of back