Gout Flashcards
1
Q
P
A
Hyperuricaemia
Deposition of sodium urate crystals in synovial fluid of joint
Inflammatory monoarthropathy
Commonly first metatarsophalygeal joint of big toe
Can be polyarticular
Attacks may be precipitated by trauma, surgery, starvation, infection, diuretics
2
Q
A
A
Hyperuricaemia Male Seafood REd meat Alcohol Diuretics, antihypertensives, aspirin Rema; fao;ire HTN
3
Q
CF
A
Sinfle peripheral joint Excruciatingly painful Red Hot Swollen Tophi - nodular SC deposition of uric acid Uric acid kidney stones
4
Q
I
A
Joint aspiration and synovial fluid analysis:
Negatively birefringent needle shaped crystal
5
Q
Mx
A
High dose NSAID
If CI, use colchicine
Steroids may be used
Rest and levate joint
6
Q
Prevention
A
Lose weight
Avoid prolonged fast
Avoid alcohol excess
Stop smoking
If >1 attack in 12m, tophi or renal stones:
Allopurinol - reduce plasma urate
Febuxostat - if allopurinol not rtolerated - decreases uric acid
