Gonadal Hormones

Question 1

Ethinyl estradiol

Answer 1

estrogen

Question 2

Mestranol

Answer 2

estrogen

Question 3

Levonorgestrel

Answer 3

Progestin 
Plan B ( most androgenic )

Question 4

Norgestrel

Answer 4

Progestin

Question 5

Ethynodiol

Answer 5

Progestin

Question 6

Norgestimate

Answer 6

Progestin

Question 7

Desogestrel

Answer 7

Progestin (least androgenic)

Question 8

Drospirenone

Answer 8

Progestin (least androgenic)

Question 9

Transdermal patch

Answer 9

combination

Question 10

Intravaginal ring

Answer 10

combination

Question 11

Mifepristone
1.) Drug class

2. ) indication
3. ) Agent is used in combination with?

Answer 11

1.) Glucocorticoid receptor antagonist
Progesterone receptor antagonist

2. ) Abortion b/c pregnancy is not maintain in absence of progesterone
3. ) used with misoprostol

Question 12

Premarin

Answer 12

Estrogen

Question 13

Menest

Answer 13

Estrogen

Question 14

Estropipate

Answer 14

Estrogen

Question 15

Medroxyprogesterone

Answer 15

Progestin

Question 16

Norethindrone

Answer 16

Progestin

Question 17

Raloxifene

1. ) Drug class
2. ) Indication

Answer 17

1. ) selective estrogen receptor modulator (SERMs)

2. ) for treatment/prophylaxis of osteoporosis or breast cancer in post-menopausal women

Question 18

Tamoxifen

1. )Drug class
2. )Indication

Answer 18

1. ) selective estrogen receptor modulator (SERMs)

2. ) treatment and prophylaxis of breast cancer

Question 19

Bazedoxifene

1. )Drug class
2. )Indication
3. ) Only available

Answer 19

1. ) selective estrogen receptor modulator (SERMs)
2. )
   - reduces endometrial overgrowth
   - helps with hotflashes*

3.) only available in combination product called duavee

Question 20

Oxandrolone

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 20

1. ) Anabolic Androgen
2. ) May be used to treat anemia, bone pain in osteoporosis, or cachexia with associated wt. loss
3. ) Gynecomastia

Question 21

Oxymetholone

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 21

1. ) Anabolic Androgen
2. ) May be used to treat anemia, bone pain in osteoporosis, or cachexia with associated wt. loss
3. ) Gynecomastia

Question 22

Finasteride

1. ) Drug class
2. ) Indication

Answer 22

1. ) 5-α reductase inhibitor ( 5-α reductase converts to DHT- a more potent form of testosterone. Too much DHT can act as growth factor on prostate and can also cause hair loss )
2. ) BPH and male pattern baldness

Question 23

Dutasteride/Tamsulosin (combo drug→ Jayln)

1. ) Drug class?
2. ) Indication?
3. )ADR?

Answer 23

1. )5-α reductase inhibitor/alpha-1 blocker
2. ) BPH
3. ) not to be handled by females (category x)

Question 24

Enzalutamide

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 24

1. ) Androgen receptor Antagonist
2. ) reduce prostate growth and treat prostate cancer
3. ) Gynecomastia

Question 25

Flutamide

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 25

1. ) Androgen receptor Antagonist
2. ) reduce prostate growth and treat prostate cancer
3. ) Gynecomastia

Question 26

Bicalutamide

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 26

1. ) Androgen receptor Antagonist
2. ) reduce prostate growth and treat prostate cancer
3. ) Gynecomastia

Question 27

Nilutamide

1. ) Drug class
2. ) Indication
3. ) ADR?

Answer 27

1. ) Androgen receptor Antagonist
2. ) Reduce prostate growth and treat prostate cancer
3. ) Gynecomastia

Question 28

Degarelix

1. ) Drug Class?
2. ) Indication?

Answer 28

1. ) GnRH receptor Antagonist

2. ) To treat advanced prostate cancer