Adrenergics Flashcards
Guanfacine
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-2 agonist
- ) ADHD (hyperactive control)
- ) extension of pharmacological profile
Brimonidine
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-2 agonist
- )eyedrops for glaucoma
- ) extension of pharmacological profile
Methyldopa
- ) Selective α-2 agonist
- )FAVORABLE drug for HTN in pregnancy**
- ) extension of pharmacological profile
Clonidine
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-2 agonist
- )HTN**; ADHD; Withdrawal
- ) extension of pharmacological profile
α-1 subtypes:
- 1A?
- 1B/1D
- 1D (specifically)
What happens when you antagonize 1A/1D?
1A→ Prostate smooth muscle contraction
1B/1D→ vascular smooth muscle contraction
1D→ Bladder neck
Antagonize 1A/1D→ BPH relief (↑ urinary flow)
Arformoterol
1.) Drug class?
1.) Selective β -2 Agonist
Indacaterol
1.) Drug class?
1.) Selective β -2 Agonist
Atomoxetine
- ) Drug class?
- ) Indication?
- ) Indirect sympathomimetic
2. )– Non-stimulant for treatment of ADHD =↑ [NE]
Terazosin
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-1 Antagonist
- ) HTN and BPH**
- ) First dose phenomenon → orthostatic hypotension
Nadolol
- ) Drug class?
- ) Indications?
- ) Non-selective β-antagonist
- )
- Glaucoma
- HTN
- Migrane prophylaxsis
- Portal HTN/esophageal varices
Alfuzosin
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-1 Antagonist
- ) BPH
- ) First dose phenomenon → orthostatic hypotension
Labetalol
- ) Drug class
- ) Indication?
- ) β-1, β-2, α-1 (ANTAGONIST)
2. ) HTN in pregnancy ***
Metoprolol
1.) Drug class?
1.) Selective β -1 Antagonists
Atenolol
1.) Drug class?
1.) Selective β -1 Antagonists
Salmeterol
1.) Drug class?
1.) Selective β -2 Agonist
Metipranolol
- ) Drug class?
- ) Indications?
- ) Non-selective β-antagonist
- )
- Glaucoma
- HTN
- Migrane prophylaxsis
- Portal HTN/esophageal varices
Tizanidine
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-2 agonist
- )HTN**; ADHD; Withdrawal
- ) extension of pharmacological profile
Alfuzosin
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-1 Antagonist
- ) BPH
- ) First dose phenomenon → orthostatic hypotension
Olodaterol
1.) Drug class?
1.) Selective β -2 Agonist
Mirabegron
- ) Drug class
- ) indication
- ) Selective β-3 agonist (detrusor)
2. ) Overactive bladder → drug will increase bladder capacity during storage phase
Isoproterenol
- ) Drug class?
- ) Indication?
- ) Non-selective β-agonist
2. ) for β-1 effect (positive inotrope)
Doxazosin
- ) Drug class
- ) Indication
- ) ADR
- ) Selective α-1 Antagonist
- ) HTN and BPH**
- ) First dose phenomenon → orthostatic hypotension