Gomori Methenamine silver

Question 1

What is the primary purpose of Gomori Methenamine silver staining?

Answer 1

• It is used to detect fungi in tissue.

Question 2

What does Gomori Methenamine silver (GMS) staining demonstrate besides fungi?

Answer 2

• Gomori Methenamine silver (GMS) staining can also demonstrate melanin.

Question 3

Why is Gomori Methenamine silver (GMS) staining considered the best permanent mount for certain applications?

Answer 3

• Gomori Methenamine silver (GMS) staining is considered the best permanent mount for its ability to detect fungi effectively.

Question 4

Describe the appearance of fungi in histologic sections stained with GMS.

Answer 4

• fungi appear brown to black, with black outlines
• The internal parts of the fungi stain pink-black
• while the background stains light green

Question 5

Why are GMS-stained sections essential in tissue pathology, especially in cases involving Candida and Aspergillus?

Answer 5

• They can detect Candida and Aspergillus, which may be missed in H & E stained sections.