CSF

Question 1

What is the primary purpose of submitting CSF for detection of C. neoformans?

Answer 1

• To detect C. neoformans in suspected fungal meningitis.

Question 2

In which population is C. neoformans considered an agent of fungal meningitis?

Answer 2

• C. neoformans is considered an agent of fungal meningitis
• In immunocompromised individuals.

Question 3

How can the collected CSF sample be processed for analysis?

Answer 3

• The collected sample can be processed either through filtration or sedimentation.

Question 4

What is the procedure if the CSF sample is processed through sedimentation?

Answer 4

• If processed through sedimentation, the sample needs to undergo centrifugation
• Resulting in sediments used for smear preparation and culture
• While the supernatant fluid is used for serology.

Question 5

What is the specification for the filter diameter if CSF is processed through filtration?

Answer 5

• If processed through filtration, a 4 diameter of 0.45 micra filter is used.

Question 6

Why is the supernatant fluid collected during sedimentation processing used for serology?

Answer 6

• Collected for serology to perform further diagnostic tests related to the condition.

Question 7

What is the recommended priority for using the second tube when collecting CSF (Cerebrospinal Fluid) samples?

Answer 7

• The second tube is prioritized for microbiological testing when collecting CSF samples.