Golgi Apparatus Flashcards
Why is membrane trafficking important?
Allows plasma membrane (PM) to alter composition of proteins and other compositions to adapt to change in the einvironment.
What are the two processes that alter the PM?
Endocytosis and Exocytosis.
Endo - transport into the cell
Exo - transport out the cell
PM components such as proteins, carbohydrates and lipids.
Function of transport vesicles?
A structure used to transport contents around the cell.
What is the process of a vesicle fusing with a membrane?
Intravesicular trafficking.
Three types of TV (transport vesicle) coating. What are they known as?
- Clathrin (Plasma Membrane)
- COPI (Golgi Apparatus)
- COPII (ER)
Functions of Golgi complex…
- modify proteins
- lipids from ER
- processed to PM, endosomes and secretory vesicles
- interacts with endocytosis
- carbohydrates synthesis
What is glycosylation?
The addition of carbohydrates to proteins.
What types of modification are added to proteins?
- protein folding
- increased solubility
- resistance to enzymatic digestion.
What is an oligosaccharide?
A polysaccharide that is made up a relatively small amount of monosaccharides.
- Short chained polysaccharide
Golgi transports its contents in two ways. They are…
- ) Vesicular transport
2. ) Cisternal maturation model
Where are macromolecules usually digested in the cell?
Area’s surrounding lysosomes.
What happens to molecules involved in endocytosis?
- ) Trafficked to the PM for recycling.
- ) Directed to a different area of the PM (transcytosis)
- ) Taken to a lysosome for degradation via early endosomes.
What happens to molecules involved in exocytosis?
Directed to:
- PM
- Secretory vesicles
Which pathway requires a intracellular signalling?
Secretory pathway
