Glycolysis Part 2

Question 1

Glycolysis “_____”

Answer 1

“Sweet Breaking”

Question 2

Stage 1 of Glycolysis

Answer 2

Entrapment

Question 3

Entrapment

Answer 3

Glucose being phosphorylated by Hexokinase

Question 4

What type of binding does Hexokinase use?

Answer 4

Induced Fit

Question 5

G6P to F6P is an example of a

Answer 5

reversible isomerization reaction

Question 6

Entrapment Part 2

Answer 6

F6P is phosphorylated to F1,6P

Question 7

Last Stage of Stage 1

Answer 7

Dihydroxyacetone phosphate(DHP) > Triose phosphate isomerase > Glyceraldehyde 3-phosphate (GAP)

Question 8

TPI causes lethal anemia and neuronal problems why?

Answer 8

Red blood cells arent able to generate their own enerdy. rely on glycolysis

Question 9

The purpose of Stage 1 is to

Answer 9

break down glucose 6C to two trioses in the cytoplasm

Question 10

ATP count after Stage 1

Answer 10

2 ATP Used, 0 ATP made

Question 11

First reaction of Stage 2

Answer 11

the formation of 1,3 bisphosphoglycerate (1,3BPG) by GAPDH

Question 12

1,3 BPG is made exergonic through

Answer 12

Thioester Intermediate

Question 13

1,3- BPG has a high level of free energy of

Answer 13

Hydrolysis/Phosphoryl Transfer Potential

Question 14

Phosphoglycerate Kinase makes

Answer 14

2 ATP

Question 15

Substrate level phosphorylation is so named because

Answer 15

the phosphate comes from the substrate and NOT ATP as usually occurs with kinases.

Question 16

GAP (aldehyde)

Answer 16

product of triose phosphate isomerase (TPI)

Question 17

3-PG (3-phosphoglycerate)

Answer 17

product of phosphoglycerate kinase

Question 18

Pyruvate Kinase makes

Answer 18

2 ATP

Question 19

PEP to Pyruvate Step drives

Answer 19

glycolysis

Question 20

After Stage 2 of Glycolysis

Answer 20

2 ATP used, 2 Net ATP Made, 2 NADH Made, 2 Pyruvate

Question 21

Glycolysis is thermodynamically…

Answer 21

favorable

Question 22

Alcoholic Fermentation

Answer 22

microbes metabolize pyruvate to EtOH

Question 23

hexokinase

Answer 23

catalyses first step of glycolysis and is allosterically inhibited by its product glucose 6-phosphate

Question 24

phosphoglycerate kinase (PGK)

Answer 24

substrate level phosphorylation, up regulated in cancer cells due to hypoxia

Question 25

phosphofructokinase (PFK)

Answer 25

catalyzes the most regulated step in glycolysis

Question 26

High Energy Charge

Answer 26

HIGH ATP, turn off and on pathway either anabolic or catabolic

Question 27

Low Energy Charge

Answer 27

LOW ATP,turn off and on pathways either anabolic or catabolic