Gluconeogenesis & Cori Cycle

Question 1

liver can MAKE glucose in

Answer 1

gluconeogenesis

Question 2

Gluconeogenesis is an_____ pathway

Answer 2

anabolic

Question 3

Gluconeogenesis means

Answer 3

“sweet, new beginning”

Question 4

Gluconeogenesis occurs in the …

Answer 4

cytoplasm

Question 5

NEED GLUCONEOGENESIS FOR

Answer 5

HIGH ENERGY DEMAND IN MUSCLES OR STARVATION/SLEEP

Question 6

Why is Energy Needed to Make Gluconeogenesis Go?

Answer 6

the opposite thermodynamic direction of glycolysis. “Up Hill” reaction

Question 7

Gluconeogenesis is NOT

Answer 7

the reversal of Glycolysis

Question 8

Gluconeogenesis Starts with

Answer 8

Pyruvate Carboxylase

Question 9

Oxaloacetate is Transported Out of the Matrix as

Answer 9

Malate

Question 10

Oxaloacetate is Converted to

Answer 10

PEP (High Energy) via PEP Carboxylase

Question 11

PEP is Converted to

Answer 11

3-Phosphoglycerate

Question 12

Phosphoglycerate Kinase Makes

Answer 12

1,3-BPG…in reverse

Question 13

Fructose 1,6-bisphosphate is

Answer 13

Dephosphorylated

Question 14

Glucose 6-phosphate is

Answer 14

Dephosphorylated to Glucose in the ER in the Liver

Question 15

In Cori Cycle, Pyruvate is Reduced to

Answer 15

Lactate in Hard-Working (Anaerobic) Muscles

Question 16

Low energy charge (ATP) stimulates

Answer 16

catabolism

Question 17

Low energy charge (ATP) inhibits

Answer 17

anabolism

Question 18

High energy charge (ATP) inhibits

Answer 18

catabolism