Glycolysis Flashcards
Step 1, reactants, products, enzyme, if irreversible or ATP required/released.
- Glucose -> Glucose-6-phosphate
- Hexokinase
- 1 ATP needed
- Irrereversible
Step 2, reactants, products, enzyme, if irreversible or ATP required/released.
- Glucose-6-phosphate -> fructose-6-phosphate
- Phosphohexose isomerase
Step 3, reactants, products, enzyme, if irreversible or ATP required/released.
-Frucose-6-phosphate -> fructose-1,6-bisphosphate
-Phosphofructokinase 1
irreversible, the committed step.
-ATP needed
Step 4, reactants, products, enzyme, if irreversible or ATP required/released.
- Fructose-1,6-bisphosphate -> dihydroxyacetone phosphate + glyceraldehyde-3-phosphate
- Aldolase
Step 5, reactants, products, enzyme, if irreversible or ATP required/released.
- Dihydroxyacetone phosphate -> glyceraldehyde-3-phosphate
- Triose phosphate isomerase
Step 6, reactants, products, enzyme, if irreversible or ATP required/released.
- Glyceraldehyde-3-phosphate + Pi -> 1,3-bisphosphoglycerate
- Glyceraldehyde-3-phosphate dehydrogenase
- NAD+ -> NADH + H+
Step 7, reactants, products, enzyme, if irreversible or ATP required/released.
-1,3-bisphosphoglycerate -> 3-phosphoglycerate
-Phosphoglycerate kinase
1 ATP released (2 total)
Step 8, reactants, products, enzyme, if irreversible or ATP required/released.
- 3-phosphoglycerate -> 2-phosphoglycerate
- Phosphoglycerate mutase
Step 9, reactants, products, enzyme, if irreversible or ATP required/released.
- 2-phosphoglycerate -> phosphoenolpyruvate
- Enolase + H2O
Step 10, reactants, products, enzyme, if irreversible or ATP required/released.
- Phosphoenolpyruvate -> pyruvate
- Pyruvate kinase
- Irreversible
Irreversible steps
1, 3, and 10.
Steps requiring ATP
1 and 3.
Step releasing ATP
7.
Step releasing NADH
6.