Glutamīnerģiskā sistēma Flashcards

1
Q

NMDA

A

eksogēnais agonists saistās pie NMDA receptora

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2
Q

glutamāts

A

glutamāterģiskās sistēmas endogēnais agonists

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3
Q

AMPA

A

eksogēnais agonists saistās pie AMPA receptora

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4
Q

Kainats

A

eksogēnais agonists saistās pie kainata receptora

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5
Q

esketamīns

A

NMDA antagonists - ievadnarkoze, vispārējā narkoze, reģionālā un vietējā anastēzija, samazina depresijas simptomus

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6
Q

memantīns

A

NMDA antagonists - alchemiera slimības ārstēšanai

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7
Q

ketamīns

A

NMDA antagonists var izraisīt halucinācijas

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8
Q

parampanels

A

AMPA antagonists - pretepilepsijas zāles, samazina neiralo aktivitāti)

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9
Q

fenciklidīns

A

NMDA antagonists - halucinogēna iedarbība

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10
Q

Metabotropie glitamāta receptori

A

mGLU1-8; mGLU6 atrodas tīklenē

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