glucose metabolism Flashcards

1
Q

what is hypoglycemia?

A

too much insulin

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2
Q

what two therapy are for hypoglycermia?

A
glucose replacement (non insulin)
anti-hypoglycemic therapy (insulin related)
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3
Q

what are the non insulin drugs?

A

dextrose
glucagon
dietary management

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4
Q

what is commonly used in emergency therapy for hypolgycemia?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate (somatostatin)

A

dextrose

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5
Q

what opens K channels in B-cells which turns off voltage gated Ca channel and inhibits insulin secretion?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate

A

diazoxide

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6
Q

what selectively destroys Bcells in pancrease and can cause nephrotoxicity?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate(somatostatin)

A

streptozotocin

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7
Q

what inhibits glucagon and insulin release from islet cells and decrease growth hormone?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate(somatostatin)

A

octerotide acetate

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8
Q

what is used for gastrinomas in dogs, cats?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate(somatostatin)

A

octerotide acetate(somatostatin)

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9
Q

what is used for acromegally, chylothroax and unsulinomas?

a. diazoxide
b. dextrose
c. streptozotocin
d. octerotide acetate(somatostatin)

A

d.octerotide acetate(somatostatin)

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10
Q

what are the insulin related therapy for hypoglycemia?

A

glucocrticoids
diazoxide
streptozotocin
somatostatin( octerotide acetate)

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11
Q

what is drug of choice for insulinoma patientsa. diazoxide

b. dextrose
c. streptozotocin
d. octerotide acetate(somatostatin)

A

diazoxide

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12
Q

A dog showing neurologic signs caused by hypoglycemia (glucose is 40 mg/dl) associated with elevated insulin concentration in blood. Which of the following drugs may be effective orally in elevating blood glucose levels MAINLY by inhibiting pancreatic insulin secretion?

a. glucagon
b. epinephrine
c. diazoxide
d. prednisone

A

diazoxide

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