Glucose/Dextrose Flashcards
1
Q
When is glucose indicated for use?
A
- 5% - intravenous water and drug reconstituition
- 10/20/50% - treat hypoglycaemia and hyperkalaemia
2
Q
What is the mechanism of action of IV glucose?
A
Glucose makes fluid isotonic and prevents osmolysis initially. It is then rapidly taken up by cells and metabolised, leaving free hypotonic water that diffuses throughout all body water compartments
3
Q
How much glucose is left in the intravascular space following IV administration?
A
Approximately 7%
4
Q
What are adverse side effects of IV glucose administration?
A
- 50% - irritant to veins
- Hyperglycaemia
5
Q
What can administration of IV glucose to those with thiamine deficiency precipitate?
A
WErnicke’s encephalopathy
