Bromocriptine and other dopaminergic drugs Flashcards
1
Q
What are indications for the use of bromocriptine and cabergoline?
A
- Prolactinoma
- Acromegaly
- Suppression/prevention of lactation
2
Q
What are contraindications for the use of cabergoline/bromocriptine?
A
- Hypersensitivity to ergot derivatives
- Cardiac valvulopathy
- Pre-eclampsia
- Hypertension in post-partum women
3
Q
When would you want to be cautions when using cabergoline/bromocriptine?
A
- History of peptic ulcer disease (GI bleeding can occur)
- Raynaud’s syndrome (vasospasm can occur)
- Cardiovascular disease
- History of serious mental illness (psychosis can occur)
- Acute porphyria
- Pregnancy and Breastfeeding
4
Q
What is the mechanism of action of bromocriptine and cabergoline?
A
Dopamine agonists
5
Q
What are common side effects of cabergoline/bromocriptine use?
A
- Headache
- Nasal congestion
- GI upset
- Hallucinations
6
Q
What are rare side effects of cabergoline/bromocriptine use?
A
- Fibrotic reactions
- Valvular disease
- Daytime sleepiness/sudden onset sleep
- Hypotensive reactions
- Peptic ulcers
- Psychosis
- Arrythmias
7
Q
What drugs can bromocriptine/cabergoline interact with?
A
Anti-hypertensive drugs
