Glucagon Flashcards

1
Q

Classification of Glucagon

A

Anti-Hypoglycaemic

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2
Q

MOA of Glucagon

A

-Stimulates release of Glycogen (Gluconeogenesis) from the liver for Glycogenolysis (inc. BGL)

-Smooth muscle relaxation

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3
Q

Indications of Glucagon

A

Hypoglycaemia (BGL <4.0 mmoL/L & unable to take oral glucose or IV d50w

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4
Q

Contraindications for Glucagon

A

-Hypersensitivity
-Pheochromocytoma (tumour in adrenal gland)

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5
Q

Dose for Glucagon

A

Hypoglycaemia:
Adults- 1mg IM, SQ, may repeat in 20 minutes if required

Pediatric- 0.5mg IM, SQ (<20kg)

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6
Q

Side effects of Glucagon

A

-Nausea
-Vomiting
-Rebound Hyperglycemia
-Hypotension
-Tachycardia

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7
Q

Precautions for Glucagon

A

-Effective only if there are sufficient stores of Glycogen within the Liver

-Use with Caution in patients with Cardiovascular or Renal Disease

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