Glomerulonephritis Flashcards
Teenage boy presents with sore throat & macroscopic haematuria ( gross ), what’s your diagnosis?
IgA nephritis
What is the most common cause of gross hsematuria in children?
IgA nephritis
> in males
Urine can be frankly bloody or the color of cola
Usually painless
Resolve spontaneously in 5 days
What do you see on renal biopsy for an igA nephritis ptn?
Mesangial igA deposition on immunofluorescence
Mesangial hypercellularity and matrix expansion on light microscopy
Q- ptn developed URTI then one day later developed edema, hematuria and elevated serum creatinine, what’s your diagnosis?
Acute glomerulonephritis caused by { IgA nephropathy or Berger’s disease }
S&S ( edema+hematuria +renal failure)
A-Palpable purpura + acute glomerulonephritis, what’s your diagnosis?
Henoch-schonlein purpura (HSP)
A- what’s the cause of idiopathic glomerulonephritis?
Rapidly progressive glomerulonephritis
A-glomerulonephritis + pulmonary hemorrhage ( in 50% ) what’s your diagnosis?
Goodpasture’ s syndrome
A- sinusitis + glomerulonephritis, what’s your diagnosis?
Wegener’s granulomatosis
What’s the difference b/w Buerger’s disease and berger’s disease?
Buerger’s = vasculitis
Berger’s = glomerulonephritis
How to treat ptn with Goodpasture syndrome?
Cyclophosphamide + corticosteroids + plasmaresis
Name the syndrome ( vasculitis + purpura + arthralgia + abd. Pain + glomerular nephritis?
Henoch-Scholein purpura
Henoch-scholein purpura is an immune complex disease involving which immunoglobulin?
IgA
Q. Young adult ptn presents with sudden onset of mild hematuria + proteinuria + azotemia + salt & water retention ( hypertension) .What’s the most likely diagnosis?
Focal segmental glomerulosclerosis
A. What’s the most common idiopathic nephrotic syndrome among adults?
FSGS
A. Name the 2ry causes of FSGS ? 4
Heroine use, obesity, nephron loss as in nephrectomy, HIV
