Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Renal > Glomerular Disease > Flashcards

Glomerular Disease Flashcards

1
Q

Criteria of Nephrotic Syndrome

A

-proteinuria (>3.5)
-hypoproteinemia
-pitting edema (hypoalbuminemia)
-hypercholestremia (hepatic lipogenesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the character of proteinuria

A

-frothy urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Criteria of Nephritic Syndrome

A

-hematuria (RBC cast)
-oligouria
-azotemia (BUN>18, Cr>1.2)
-hypertension
-mild proteinuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the nephrotic syndrome diseases

A

MF MDA
-minimal changes
-focal segmental glomerulosclerosis
-membranous nephropathy
-diabetic
-amyloidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the nephritic syndrome diseases

A

-APSGN
-RPGN (cresenteric)
-IgA nephropathy (Burger)
-Alport syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the characteristic edema in nephrotic syndrome

A

-generalized edema with periorbital edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is proteinuria

A

Protein in urine more than 100mg/m2/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the test to diagnose proteinuria

A

-urine dipstick
-24 hour urine collection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the most cause of nephrotic syndrome

A

-minimal changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In minimal changes disease, what is the main changes occuring in EM

A

-effacement of the pedocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Why steroid is given in minimal changes disease

A

-it will prevent the T cell to release cytokine that will cause damage to the podocyte and GBM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the people at risk of FSGS

A

-heroin drug abuser
-black people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happened to untreated Focal Segmental GS patient

A

-it will worsen to ESKD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the L/M findings of focal segmental GS

A

-sclerosis
-hyalinosis
-lipid laden (foamy) macrophage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the cause of focal segmental GS

A

-primary (idiopathic)
-secondary (drug abuser; HIV, heroin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the cause of thickening in membrane nephropathy

A

-deposition of immune complex in the subepithelial

17
Q

What is the second most common cause of nephrotic syndrome in adult

A

-membrane nephropathy

18
Q

What is the complication of membrane nephropathy

A

-DVT
-RVT

19
Q

What is the IF manifestation of membrane nephropathy

A

-granular
-subepithelial immunocomplex deposition

20
Q

What is the IF manifestation of membrane nephropathy

A

-granular
-subepithelial immunocomplex deposition

21
Q

What is the EM manifestation of membrane nephropathy

A

-spike and dome with silver stain

22
Q

In diabetic nephropathy, how does proteinuria occurs

A

-diabetic causes deposition of type IV collagen
-leading to thickening of the vessel
-which increase the permeability to protein

23
Q

In diabetic nephropathy, what causes severe proteinuria (>4)

A

-diffuse mesangial sclerosis

24
Q

What is Kimmelstiel-Wilson lesion

A

-it is a eosinophilic nodular glomerulosclerosis
-it present in diabetic nephropathy

25
Q

What is the definition of hematuria

A

The presence of RBC >6 on light microscope or > 3 consecutive sample

26
Q

A history of a children with a history of streptococcal skin infection (scarlet fever) returns to the hospital after 2-4 weeks of having the condition due to present of blood in urine

A

-APSGN

27
Q

Subepithelial IC hump (lumpy-humpy) is mainly found in case of

A

-APSGN

28
Q

What is the etiology of crescentic GN wirg linear immune complex deposition

A

-goodpasture syndrome

29
Q

What is the etiology of crescentic GN wirg granular subepithelial immune complex deposition

A

-ASPGN (lumpy-bumpy, dome shape)

30
Q

What is the etiology of crescentic GN with granular subendothelial immune complex deposition

A

-DPGN

31
Q

What is the etiology of crescentic GN without immune complex deposition

A

-pauci immune

32
Q

A history of a children with a history of UTI and after 1-3 days, the patient notices the present of blood in urine occuring cocurrently

A

IgA nephropathy (Berger)

33
Q

What is the main symptoms of IgA nephropathy

A

-synpharyngitis (concurrent infection), -macroscopic hematuria (gross)

34
Q

What is the most associated condition with IgA nephropathy

A

-henoch scholein purpura

Renal (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions