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Ama - Diabetes mellitus > Gliptins > Flashcards

Gliptins Flashcards

1
Q

DPP4 inhibitors (Gliptins)

A

DPP-4 breaksdown the hormone incretin
Incretin is made by the gut in response to food - increase insulin secretion and lower glucagon secretion

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2
Q

Examples

A

Alogliptin
Linagliptin
Saxagliptin
Sitagliptin
Vildagliptin

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3
Q

Side effects

A

Pancreatitis
Counsel patients to report severe, abdominal pain

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4
Q

Renal impairment

A

Dose reduction or caution (NOT linagliptin)

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5
Q

Hepatic impairment

A

Dose reduction or caution or AVOID
(not for linagliptin + sitagliptin)

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Ama - Diabetes mellitus (17 decks)

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