Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Ama - Diabetes mellitus > Gliflozins > Flashcards

Gliflozins Flashcards

1
Q

Gliflozins

A

SGLT-2 inhibitors
Inhibits sodium-glucose co-transporter 2 in renal tubule = reduced glucose reabsorption = increased urinary excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Examples

A

Dapagliflozin
Empagliflozin
Canafliflozin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SE

A
  • Life-threatening atypical DKA with only moderately raised blood glucose
  • Volume depletion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Life threatening DKA

A

Moderately raised blood glucose
Stop and test for ketons if DKA suspected
Report DKA symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Volume depletion

A

Counsel pt to report:
- Postural hypotension
- Dizziness

Other SE:
- Constipation
- Thirst
- Polyuria
- UTIs
- Genital infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Canagliflozin

A

MHRA/CHM
- Increased risk of lower limb amputation (mainly toes)

Counsel pt to report:
- Skin ulceration
- Discolouration
- New pain

Stay hydrated, preventative foot care, recognise/treat foot problems early

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Gliflozins - MHRA

A
  • DKA
  • Necrotising fasciitis of the genitalia
  • Not to be used for T1DM (dapagliflozin)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Ama - Diabetes mellitus (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions