Glaucoma Flashcards

1
Q

what is glaucoma?

A

progressive optic neuropathy due to high IOP caused by blockage of aqueous humour drainage

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2
Q

what is optic neuropathy?

A

damage to the optic nerve

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3
Q

two types of glaucoma

A
  1. closed angle (AACG)

2. open angle

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4
Q

what is closed angle glaucoma?

A

angle is blocked by iris being pushed forward due to fluid increase in posterior chamber

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5
Q

what must be done in AACG

A

pressure must be reduced to avoid blindness

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6
Q

what precipitates AACG?

A

NA
mydriatics
anticholinergics
tricyclics

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7
Q

presentation of AACG

A
red eye
sudden visual loss with blur
halos around lights
headache, N&V due to extreme pain
cloudy cornea
dilated pupil (ischaemia of sphincter pupillae)
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8
Q

management of AACG

A

drops to lower IOP

laser iridotomy

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9
Q

what drops lower IOP?

A
pilocarpine
hyperosmotic agents e.g. glycerol and mannitol
timolol
brimonidine
acetazolamide
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10
Q

what is open angle glaucoma?

A

trabecular meshwork becomes clogged so fluid cannot escape and pressure builds

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11
Q

presentation of open angle

A

often asymptomatic

can have visual field defect or tunnel vision

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12
Q

appearance of fundoscopy of open angle glaucoma

A

cupped disc due to loss of retinal ganglion cells in neuro-retinal rim

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13
Q

diagnosis of open angle

A

visual fields
Goldmann applanation tonometry
fundoscopy

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14
Q

pharmacological management of open

A

beta blockers
CA inhibitors
prostaglandin analogues (FIRST LINE)
alpha-adrenergic agonists

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15
Q

surgery options in open

A

trabeculopathy (open angle to open meshwork)

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16
Q

what drugs decrease production of aqueous humour?

A

beta blockers e.g. timolol

CA inhibitors e.g. dorzolamide

17
Q

which drugs increase outflow of aqueous humour

A

prostaglandin-analogues e.g. latanoprost

18
Q

adverse of latanoprost

A

eyelash growth

eyelid and iris pigmentation (browning)

19
Q

which drugs decrease production and increase outflow

A

sympathomimetics e.g. alpha-adrenergic agonists - brimonidine