GIT pathogens - Bacteria - Intoxication Flashcards
Staph aureus incubation period
2-6 hours
Bacteria causing intoxication: 1) 2) 3) 4)
1) Staphylococcus aureus
2) Bacillus cereus - emetic type
3) Bacillus cereus - diarrhoeal type
4) Clostridium perfringens
Bacillus cereus emetic type incubation period
1-5 hours.
Bacillus cereus diarrhoeal type incubation period
6-15 hours.
Clostridium perfringens incubation period
6-24 hours.
Staph aureus associated foods
Salty or sugary foods.
Bacillus cereus emetic type associated foods
Rices, pulses
Bacillus cereus diarrhoeal type associated foods
Meat, dried vegetables, milk products, soup.
Clostridium perfringens associated foods
Fish, poultry, beef, sauces, gravy.
Staph aureus toxin type
Heat-stable enterotoxin (types A, B, C, D, E, F, G).
Heat-stable enterotoxin mods of action
Binds neural receptors in upper GIT. Stimulates vomiting centre in the brain.
Bacillus cereus emetic type toxin
Heat-stable cereulide toxin.
Bacillus cereus diarrhoeal type toxin
1)
2)
1) Heat-labile toxin - Haemolysin BL.
2) Enterotoxin Nhe.
Enterotoxin Nhe mode of action
Increase adenylate cyclase concentration.
Increased intestinal fluid secretion.
Clostridium perfringens toxin mode of action.
Inhibits glucose transport in lumen.
Intestinal cells damaged, protein loss to lumen.
