giant cell tumour of bone Flashcards
1
Q
what is it?
A
benign tumour arising from giant cells of bone marrow
2
Q
what is pathophysiology?
A
occur in metaphyseal region, involve epiphysis and can extend to subchondral bone adjacent to joint
locally aggressive
3
Q
what is the clinical presentation?
A
painful mass/swelling
pathological fracture
4
Q
where in the body do they commonly occur?
A
around knee and in distal radius, can occur in long bones, pelvis and spine
5
Q
what investigations are used?
A
x-ray, histology
6
Q
what is the buzzword for x-ray result?
A
soap bubble appearance
7
Q
what is shown on histology?
A
multi-nucleated giant cells
8
Q
A
